FCS - Capítulos de Livros em Editoras Internacionais
Permanent URI for this collection
Browse
Browsing FCS - Capítulos de Livros em Editoras Internacionais by Title
Now showing 1 - 10 of 24
Results Per Page
Sort Options
- Adrenaline and noradrenaline: partners and actors in the same playPublication . Marisa, Vera; Carvalho, Félix; Bastos, Maria Lourdes; Albuquerque, Rui; Carvalho, Márcia; Remião, Fernando
- Advances in nanoparticulate carriers for oral peptides and proteins: polymeric vs. lipid nanoparticlesPublication . Silva, Ana Catarina; Santos, D.; Ferreira, D.C.; Souto, Eliana B.
- Bagaço de uva com potencial nutracêutico e aditivo em produtos alimentaresPublication . Ferreira da Vinha, AnaOs subprodutos da indústria vitivinícola nacional, embora subvalorizados, constituem uma fonte de nutrientes e de compostos bioativos, potenciando-os como aditivos naturais. Reduzir a perda e o desperdício de alimentos é um dos grandes desafios para a reciclagem de recursos naturais e para o avanço de sistemas alimentares sustentáveis. Assim, algumas das dinâmicas científicas na gestão de resíduos alimentares incluem a valorização de subprodutos como fonte de compostos fenólicos para formulação de alimentos funcionais. Touriga Nacional é uma casta de uva tinta originária de Portugal. É a rainha das uvas portuguesas e que pelas suas qualidades para a vinificação, começa a ocupar cada vez mais espaço nas produções europeias, australianas e californiana. Alvarinho é uma casta branca, sendo a mais nobre das castas brancas do noreste ibérico, capaz de produzir um vinho de elevadíssima qualidade. Ambos os bagaços, enquanto subprodutos, apresentaram teores elevados de nutrientes (cinzas, proteína total, lípidos e carbohidratos). Por outro lado, também possuem teores consideráveis de fenólicos e flavonoides totais (25-41 mg EAG/g e 9,2-18 mg EC/g, respetivamente). Como era expectável, o teor de antocianinas foi evidenciado apenas no bagaço de uva tinta (37 mg/g), bem como a presença dos ácidos vanílico e siríngico. A quercetina, enquanto flavonoide, foi encontrada apenas na casta branca, reforçando o interesse pelos subprodutos das uvas brancas, uma vez que este flavonoide apresenta propriedades antioxidantes, anti-inflamatórias, antiproliferativas, propriedades antineoplásicas, antidiabéticas e antimicrobianas, podendo ter interesse como aditivo alimentar e/ou ingrediente nutracêutico na indústria alimentar.
- Bioactive lipids: pharmaceutical, nutraceutical, and cosmeceutical applicationsPublication . Fernandes, Eduarda; Lopes, Carla Martins; Lúcio, Marlene
- Biochemical changes in cardiovascular diseasesPublication . Moutinho, Carla; Matos, Carla; Silva, Carla Sousa e
- Biological activities and valuable bioactive compounds from portuguese medicinal plantsPublication . Ferreira da Vinha, Ana; Silva, Carla Sousa eCurrently, there are more than 85,000 plant species that have been documented for medical use globally. This implies, plant derived natural products hold great promise for discovery and development of new pharmaceuticals in diverse human ailments. The lack of effective pharmaceutical formulas and the resistance created by current antibiotic pathogens, as well as oxidative stress new therapeutic agents from plants. In fact, several studies have shown that medicinal plants possess antioxidant properties due largely to their phytochemical profile. Endemic plants can be a source of new bioactive compounds able to prevent several diseases such as cancer, diabetes, hypertension, and Alzheimer’s disease by combating oxidative stress and its associated pathologies. The purpose of this study was to evaluate the contents of total phenolics, flavonoids, and caffeine in six medicinal plants used traditionally in phytotherapy, usually consumed as tea or infusion namely: Camellia sinensis, Melissa officinalis, Lippia citriodora, Cymbopogon citratus, Matricaria chamomilla, and Tilia cordata. Significant variations in total phenolics and flavonoids content were found among analyzed plants and depending on the nature of the extract. The concentration of caffeine was also very dissimilar and followed the sequence M. officinalis < T. cordata < C. citratus < M. chamomilla < L. citriodora < C. sinensis. Also, the antioxidant activity of each plant was found to vary according to C. citratus (90.9%) > C. sinensis (87.8%) > M. officinalis (50.7%) > M. chamomilla (45.3%) > T. cordata (32.2%) > L. citriodora (28.0%).
- Challenges in nanomaterials characterization - from definition to analysis (capítulo 1)Publication . Catita, JoséNanomaterials have outstanding properties and have several applications, ranging from foods, cosmetics, pharmaceuticals to energy, construction, etc. As with all novel products, the benefits of nanomaterials use must be weighed against its health and environmental impact. They have different origins, natural, incidental, or engineered, they are widespread, and they need to be classified and characterized for various purposes, including nanotoxicology studies and risk assessment, workplaces and environment safety evaluation, consumer products evaluation, as well as manufacturing process control. To properly characterize nanomaterials, a consensual definition of nanomaterial is needed, and several analyses using the available characterization techniques must be performed. Various properties are relevant in the characterization process and many of them, namely size, are still a challenge that the research community is facing. The measurement of physical and chemical properties is very important in the case of nanomaterials. In view of this, in this chapter, available analytical techniques are reviewed based on nanomaterials classification, regulatory demands and toxicology assessment. Additionally, some of the current major challenges and gaps in nanomaterials characterization are identified and listed.
- Chapter 3 - General aspects of multifunctional nanosystemPublication . Lúcio, Marlene; Real Oliveira, Maria Elisabete; Lopes, Carla Martins
- Chapter 4 - Organic nanocarriers for brain drug deliveryPublication . Lúcio, Marlene; Lopes, Carla Martins; Fernandes, Eduarda; Gonçalves, Hugo; Real Oliveira, Maria ElisabeteAlthough the blood–brain barrier remains a major barrier to drug delivery, organic nanocarriers (ONCs) have been demonstrated to be effective in targeting and delivering therapeutic agents to the brain and have provided promising preclinical outcomes. Because of their favourable physicochemical properties, such as biocompatible composition, nanometric dimensions, large surface area compared to volume and easily tuneable surfaces, ONCs have proven to be excellent transport vehicles capable of prolonging drug (or other therapeutic agents) circulation time and of addressing the challenges posed by numerous diseases affecting the brain.This chapter presents an overview of the different types of ONCs for brain delivery, including a description of their advantages and disadvantages, and a set of preclinical studies illustrating the most effective strategies for effective brain distribution. Biodegradation and bioelimination issues and future challenges for effective clinical translation are also addressed.
- Chapter 5 - Lipid-based nanocarriers for co-delivery of anticancer drugs and natural compoundsPublication . Fernandes, Eduarda; Soares, Telma; Lopes, Carla Martins; Real Oliveira, Maria Elisabete; Lúcio, Marlene
- «
- 1 (current)
- 2
- 3
- »