FCS - Comunicações em Conferências Internacionais
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- Phenolic profile from the pomace of two portuguese grape varieties: sustainability and food safety as new natural additivesPublication . Ferreira da Vinha, Ana; Magalhães e Sousa, Gonçalo; Silva, Carla Sousa e; Brenha, João; Sampaio, RicardoGrapes are one of the most produced fruit crops worldwide. About 75% of produced grapes is planned for wine production, originating 20-30% waste products. This waste is mainly constituted by grape pomace which includes fruit peels, remaining pulp, seeds, and stalks. Moreover, as it is common knowledge that therapeutic properties of plants and their by-products have been increasingly described, because of their strong antioxidant values, absence of side effects, and economic viability. Synthetic antioxidants have been used as supplement added, however, their inclusion in chronic infections have confined their utilization in foods. Grape pomaces have biotechnological potential, having been applied in several studies as a fortification ingredient in foods. Reuse of the grape pomace depends on its composition and characteristics. Because grape pomace is a highly perishable product (due to the high moisture content) and given the high volumes generated during harvest season, the utilization of fresh grape pomace is unfeasible and requires an appropriate method of preservation or appropriate use. Thus, grape pomace can be reused through oil extraction, antioxidant, and antibacterial agents’ preparation and, from a nutritional perspective, polyphenols are the most important constituents. Large amounts of the residual quantities of bioactive substances remain in the vegetable tissues: phenolic acids, several flavonoids, flavanols (e.g., catechin, epicatechin and epigallocatechin) and other phenolic compounds (proanthocyanidins or condensed tannins). Considering the importance of winemaking in Portugal, the phenolic profile of two national grape pomace varieties (Touriga Nacional (red) e Alvarinho (white)) was studied, considering that the extraction of polyphenols from grape pomace represents an attractive, sustainable, and cost-effective source of high-value biological properties, which could be incorporated into foods, as natural additives. Due to the increasing demand for nutraceutical and antioxidant compounds, the study of grape pomace polyphenols exploitation may be useful for industrial purposes. Phenolic compounds were identified and quantified by Reverse-Phase High Performance Liquid Chromatography (RP HPLC) equipped with a diode array detector (HPLC-DAD).
- Agro-food wastes: valorization of lychee (Litchi chinensis) peelsPublication . Ferchal, Clemence; Silva, Carla Sousa e; Ferreira da Vinha, AnaBackground: Tropical fruits represent one of the most important crops in the world. Moreover, currently, food security is a growing problem due to the depletion of natural resources and increasing population, which has led to a gap between production and consumption (1). Nowadays, medicine has started to pay great attention to functional food, which displays an additional function related to health promotion or disease prevention. In fact, phytochemicals present in fruit byproducts (peel and seeds) are generally significantly higher than in their respective edible tissues (pulp), suggesting these wastes to be potential sources for isolating bioactive compounds or as nutraceuticals ingredients for new food products (2). Methods: Lychee (Litchi chinensis) is a very popular fruit, currently consumed worldwide. The peel and seed represent 50% of the fruit, which is considered high. However, when processed properly, such waste can generate other products as extracts and flours, contributing to its use in food, pharmaceutical and cosmetic industries. Selected fruits were washed, weighed and separated into peel, pulp and seed. The peel was lyophilized, ground, and stored protected from light until the time of analysis. Proximate composition of lychee peel flour was performed according to the methods AOAC (3), and dietary fiber, determined using enzymatic kit Sigma®, followed the technique proposed by (3). The total energy value (TEV) was also calculated. Results: Total carbohydrates and TEV were high (60 g/100 g and 318 kcal/100 g, respectively), presenting low content of proteins and lipids. Lychee peel flour presented 20 g/100 g dietary fiber. The Reference Daily Intake (RDI) is 25 g fiber (4); thus, this flour may be considered a potential fiber source, to be integrated in new products. Conclusions: It is desirable to find proper food applications for fruits peel for helping the environment through sustainability and creating new value-added food products.
- Integration of metabolomics and lipidomics for prostate cancer tissue fingerprintingPublication . Lima, Ana Rita; Carvalho-Maia, Carina; Jerónimo, Carmen; Henrique, Rui; Aveiro, S. S.; Melo, Tânia; Domingues, Rosário; Bastos, Maria de Lourdes; Carvalho, Márcia; Guedes de Pinho, Paula; Pinto, Joana
- In vitro volatile exometabolome signature of clear cell renal cell carcinomaPublication . Amaro, Filipa; Pinto, Joana; Rocha, Sílvia; Araújo, Ana Margarida; Gonçalves, Vera Miranda; Jerónimo, Carmen; Henrique, Rui; Bastos, Maria de Lourdes; Carvalho, Márcia; Guedes de Pinho, Paula
- Early pathways of toxicity triggered by 3,4-methylenedioxypyrovalerone unveiled by in vivo toxicometabolomicsPublication . Araújo, Ana Margarida; Carvalho, Márcia; Costa, Vera Marisa; Duarte, José Alberto; Dinis-Oliveira, Ricardo; Bastos, Maria de Lourdes; Guedes de Pinho, Paula; Carvalho, Félix
- Renal cell carcinoma detection by analysis of volatile organic compounds in urinePublication . Guedes de Pinho, Paula; Monteiro, M.; Moreira, N.; Jerónimo, C.; Henrique, R.; Bastos, M.; Gil, A.; Carvalho, Márcia
- βk-amphetamines: neurotoxicity triggered by methylone and MDPV in undifferentiated and differentiated SH-SY5Y cells and comparison to MDMAPublication . Valente, M.; Bastos, M.; Carvalho, F.; Guedes de Pinho, Paula; Carvalho, Márcia
- Effect of subtoxic and toxic concentrations of galactosamine in the metabolome of primary mouse hepatocytesPublication . Araújo, Ana Margarida; Lima, Ana Rita; de Lourdes Bastos, Maria; Carvalho, Félix; Carvalho, Márcia; de Pinho, Paula Guedes
- Role of autophagy, apoptosis and oxidative stress in the toxicity of β-keto amphetamines to human dopaminergic SH-SY5Y cellsPublication . Valente, Maria João; Amaral, Cristina; Correia-da-Silva, Georgina; Duarte, José Alberto; de Lourdes Bastos, Maria; Carvalho, Félix; de Pinho, Paula Guedes; Carvalho, Márcia
- Hepcidin-25 and treatment with erythropoiesis stimulating agents are independently related with erythropoiesis in chronic hemodialysis patientsPublication . Belo, Luís; Rocha, Susana; Valente, Maria João; Coimbra, Susana; Catarino, Cristina; Bronze-da-Rocha, Elsa; Carvalho, Márcia; Rocha-Pereira, Petronila; do Sameiro-Faria, Maria; Oliveira, José Gerardo; Madureira, José; Fernandes, João Carlos; Miranda, Vasco; Santos-Silva, Alice
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