Browsing by Author "Coutinho, F."
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- Antifungal activity of endemic Origanum virens from PortugalPublication . Soares, M.O.; Ferreira da Vinha, Ana; Lima, R.P.; Coutinho, F.; Catarino, P.Origanum virens is widely used in Portuguese, and Mediterranem, cuizin. Althout it is use as food condiment, it is also used in traditional medicin as antiseptic. The antifungal activity of Origanum virens essential oil on Candida albicans ATCC 10231 and physicchemical characterization of several extracts were evaluated.
- Antimicrobial activity of essential oil of Cymbopogon citratus (DC) Stapf. Poaceae-Gramineae from Angola in ATCC and multidrug resistant strainsPublication . Soares, M.O.; Ferreira da Vinha, Ana; Lima, R.P.; Coutinho, F.; Machado, M.; Catarino, P.Cymbopogon citratus (DC) Stapf. Poaceae-Gramineae (C. citratus) is an herb from India, which grows in several countries in tropical and sub-tropical, as the Republic of Angola, where tea is known as caxinde. This tea is consumed, as aromatic drink, as well as in traditional cuisine due to its lemon flavor. Cymbopogon citratus (DC) is widelly used in folk medicine, where infusions and decoctions, feature anti-spasmatic, carminatives and anti-hypertension properties. The essential oil of C. citratus is often applied, in pharmaceutical industry, as flavor and fragrance, and is also used as a source of new phytochemical molecules for the development of new pharmaceutical products.
- Antimicrobial natural productsPublication . Soares, M.O.; Ferreira da Vinha, Ana; Coutinho, F.; Pires, P.C.Our ethnopharmacological studies, in several Angolan regions, showed that Cymbopogon citratus (DC) Stapf., it´s applied in folk medicine to treat several diseases In order to validate antibacterial activity several studies were performed using 12 bacterial strains. The essencial oil samples of Cymbopogon citratus, obtained by hydro-distillation, were analysed by GC and GC-MS. Constituents were identified and tested for their antimicrobial activity by the disc agar diffusion technique and the dilution technique against Staphylococcus aureus (ATCC 25923) and Staphylococcus epidermidis (ATCC 12228) and other bacterial strains. Broad spectrum antibacterial activity was exhibited by the Cymbopogon citratus essential oil against both Gram-positive and Gram-negative bacteria as well as for MRSA that exhibited more sensitive towards the test substance compared to the non-MRSA. Our work was the first to show that Cymbopogon citratus essential oil has higher antibacterial activity against MRSA strains, than commercial antibiotics. These discover opens a new hope to fight against nosocomial infection.
- Caracterização do perfil químico e avaliação do poder redutor dos compostos antioxidantes presentes no Prunus armeniaca L. de origem portuguesaPublication . Ferreira da Vinha, Ana; Coutinho, F.; Machado, M.; Soares, M.O.O stress oxidativo produzido pelo organismo está diretamente relacionado com o aparecimento e/ou desenvolvimento de doenças crónicas. O oxigénio é um componente essencial para os seres vivos, mas a geração de espécies reativas de oxigénio (EROs) é inevitável no metabolismo aeróbio. Nas células, os EROs podem causar a oxidação de lípidos e proteínas e danos na cadeia do DNA.
- Cymbopogon citratus EO antimicrobial activity against multi-drug resistant Gram-positive strains and non-albicans-Candida speciesPublication . Soares, M.O.; Ferreira da Vinha, Ana; Barreira, Sérgio; Coutinho, F.; Aires-Gonçalves, S.; Oliveira, M.B.P.P.; Pires, P.C.; Castro, A.We studied the antibacterial and antifungal activity of Cymbopogon citratus. These properties were studied on hospital isolated multidrug resistant strains Staphylococcus aureus, Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Klebsiella pneumonia and their respective ATCC control strains. Pathogenic Candida albicans, Candida parapsilosis, and Candida tropicalis were also tested. Results of the present investigation provide evidence that the EO of Cymbopogon citratus could have a potential application in the treatment and prevention of diseases caused by Staphylococcus aureus methicillin-resistant strains and by vancomicin-resistant Staphylococcus epidermidis. Cymbopogon citratus EO is also effective against Candida albicans as well as the emerging Candida parapsilosis and Candida tropicalis pointing to its usefulness as an antifungal agent.
- Estudo comparativo das variações de licopeno, ácido ascórbico e fenólicos totais e sua interacção como compostos antioxidantes em tomates (Lycopersicon esculentum) provenientes de agriculturas convencional e orgânicaPublication . Ferreira da Vinha, Ana; Coutinho, F.; Machado, M; Soares, M.O.; Almeida-Dias, A.Um novo paradigma sobre a dieta e a saúde envolve questões que reforçam a ênfase para os aspetos positivos da dieta alimentar. Atualmente, existe um potencial mercado para os produtos orgânicos, uma vez que existe um grande desconforto por parte da população portuguesa na manutenção do consumo de certos alimentos convencionais, cujo cultivo envolve o emprego de elevados teores de adubos sintéticos e pesticidas.
- Estudo fitoterapêutico de Cymbopogum citratus de Angola: caracterização química e avaliação da actividade antioxidante e antibacteriana in vitroPublication . Soares, M.O.; Silva, A.; Coutinho, F.; Machado, M.; Herdeiro, T.; Catarino, P.; Ferreira da Vinha, AnaO Cymbopogon citratus (DC) Stapf. é cultivado em várias regiões tropicais e sub-tropicais. O seu uso na medicina tradicional abrange um ampla gama de indicações por tradição. confiança e falta de poder económico. As propriedades antimicrobianos dos óleos essenciais despertam interesse por constituírem uma alternativa para os consumidores na prática de aditivos naturais como fonte de conservação dos alimentos.
- Evolução dos compostos bioactivos e seu poder redutor em tomates biológicos e de cultivo convencionalPublication . Ferreira da Vinha, Ana; Soares, M.O.; Coutinho, F.; Santos, A.; Almeida-Dias, A.Um novo paradigma sobre a dieta e a saúde envolve questões que reforçam a ênfase para os aspetos positivos da dieta alimentar. Atualmente, existe um potencial mercado para os produtos orgânicos, no entanto, existem controvérsias sobre os mesmos, principalmente no que toca à sua classificação nutricional.
- Origanum virens endemic from Portugal: a novel antifungal activity with antioxidant capacityPublication . Soares, M.O.; Ferreira da Vinha, Ana; Coutinho, F.; Lima, R.; Catarino, P.P.Origanum virens is widely used in Portuguese cuisine. Spices are common food adjuncts, which have been used as flavoring, seasoning, and coloring agents and sometimes as preservatives throughout the world for years. Many spices have been recognized to have medicinal properties and possess many beneficial effects on health, such as antioxidant activity, digestive stimulant action, anti-inflammatory, antimicrobial, hypolipidemic, anticarcinogenic potential. Although it is use as food condiment, it is also used in traditional medicine as antiseptic.