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Estudo da composição de produtos comercializados no tratamento da obesidade: evidência científica do uso de plantas medicinais e suplementos alimentares
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| 21899 | 1.03 MB | Adobe PDF |
Advisor(s)
Abstract(s)
Introdução: A obesidade constitui um grave problema de saúde pública, devido à escassa evidência científica na utilização de plantas medicinais que ainda gera desconfiança nos profissionais de saúde, tanto no momento da prescrição como no aconselhamento. Contribuindo para tal a existência de inúmeras plantas medicinais e suplementos comercializados para o tratamento da obesidade e perda de peso, com mecanismos de ação bastante diferenciados.
Objetivos: O objetivo principal deste trabalho consistiu na revisão dos mecanismos de ação de plantas medicinais no tratamento da obesidade, tendo como base artigos de revisão integrativa ou sistemática com ou sem metanálise suportados com evidência científica das plantas referidas pelos autores. Por último pretendeu-se conhecer, com base nas plantas abordadas na presente dissertação, as plantas medicinais e suplementos alimentares comercializados em Portugal.
Metodologia: A pesquisa bibliográfica teve como objetivo obter artigos de revisão relativos ao estado da arte e revisão sistemáticas, obtendo-se assim as plantas referenciadas pelos autores como as mais utilizadas, com maior interesse na perda de peso e com maior evidência científica. Foi também realizada uma pesquisa do mecanismo de ação das 12 plantas indicadas, assim como a parte da planta com atividade farmacológica e análise dos resultados dos estudos clínicos analisados pelos autores nos autores nos artigos científicos. Finalmente, foram pesquisadas plataformas de comercialização online, para conhecer quais os produtos comercializados em Portugal que contêm as plantas estudadas.
Resultados e conclusão: Foram encontradas 12 plantas com potencial para serem incluídas em medicamentos ou suplementos alimentares para a gestão da obesidade. A maioria dos mecanismos de ação está estudada com base em estudos in vitro e in vivo.
Verificou-se uma elevada escassez de estudos clínicos para estudar a eficácia das mesmas plantas na obesidade. Apenas 8 das plantas estudadas foram encontradas em suplementos alimentares comercializados em Portugal e nenhuma se encontra comercializada como medicamento. É notória a falta de estudos clínicos que incluam plantas medicinais com potencial para o tratamento da obesidade e que possam suportar a decisão clínica e aconselhamento dos suplementos alimentares
Introduction: Obesity is a serious public health issue, due to the lack of scientific evidence on the use of medicinal plants, which still generates distrust in health professionals, both at the time of prescription and counseling. Contributing to this is the existence of numerous medicinal plants and supplements marketed for the treatment of obesity and weight loss, with very different mechanisms of action. Objective: The main objective of this work was to review the mechanisms of action of medicinal plants in the treatment of obesity, based on integrative or systematic review articles with or without meta-analysis supported by scientific evidence of the plants mentioned by the authors. Finally, it was intended to know, based on the plants discussed in this dissertation, the medicinal plants and food supplements marketed in Portugal. Methods: The bibliographic research aimed to obtain articles related to the state of the art and systematic review, thus obtaining the plants referenced by the authors as the most used, with greater interest in weight loss and with greater scientific evidence. Research was also carried out on the mechanism of action of the 12 plants indicated, as well as the part of the plant with pharmacological activity and analysis of the results of the clinical studies analyzed by the authors in the authors in the scientific articles. Finally, online marketing platforms were researched to find out which products marketed in Portugal contain the plants studied. Results and conclusion: 12 plants were found with potential to be included in drugs or dietary supplements for the treatment of obesity. Most of the mechanisms of action are studied based on in vitro and in vivo studies. There has been a high scarcity of clinical studies to study the effectiveness of the same plants in obesity. Only 8 of the plants studied were found in food supplements marketed in Portugal and none are marketed as a medicine. It is notorious the lack of clinical studies that include medicinal plants with potential for the treatment of obesity and that can support the clinical decision and advice of food supplements.
Introduction: Obesity is a serious public health issue, due to the lack of scientific evidence on the use of medicinal plants, which still generates distrust in health professionals, both at the time of prescription and counseling. Contributing to this is the existence of numerous medicinal plants and supplements marketed for the treatment of obesity and weight loss, with very different mechanisms of action. Objective: The main objective of this work was to review the mechanisms of action of medicinal plants in the treatment of obesity, based on integrative or systematic review articles with or without meta-analysis supported by scientific evidence of the plants mentioned by the authors. Finally, it was intended to know, based on the plants discussed in this dissertation, the medicinal plants and food supplements marketed in Portugal. Methods: The bibliographic research aimed to obtain articles related to the state of the art and systematic review, thus obtaining the plants referenced by the authors as the most used, with greater interest in weight loss and with greater scientific evidence. Research was also carried out on the mechanism of action of the 12 plants indicated, as well as the part of the plant with pharmacological activity and analysis of the results of the clinical studies analyzed by the authors in the authors in the scientific articles. Finally, online marketing platforms were researched to find out which products marketed in Portugal contain the plants studied. Results and conclusion: 12 plants were found with potential to be included in drugs or dietary supplements for the treatment of obesity. Most of the mechanisms of action are studied based on in vitro and in vivo studies. There has been a high scarcity of clinical studies to study the effectiveness of the same plants in obesity. Only 8 of the plants studied were found in food supplements marketed in Portugal and none are marketed as a medicine. It is notorious the lack of clinical studies that include medicinal plants with potential for the treatment of obesity and that can support the clinical decision and advice of food supplements.
Description
Keywords
Plantas medicinais Obesidade Fitoterapia Perda de peso Medicinal plant Obesity Phytotherapy Weight loss