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Biomarcadores de contaminaĆ§Ć£o ambiental
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| PPG_29729 | 996.42 KB | Adobe PDF |
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Abstract(s)
A presenƧa de um xenobiĆ³tico no ambiente representa sempre um risco para os organismos vivos e para o meio onde estes habitam. Um dos mĆ©todos para avaliar a exposiĆ§Ć£o aos xenobiĆ³ticos e o seu potencial impacto sobre os seres vivos baseia-se na utilizaĆ§Ć£o dos chamados biomarcadores. Estes podem fornecer indicaƧƵes da exposiĆ§Ć£o, efeito e suscetibilidade individual a compostos quĆmicos ambientais e sĆ£o ferramentas muito Ćŗteis para avaliar e controlar o risco de danos a longo prazo associados Ć exposiĆ§Ć£o a xenobiĆ³ticos, tais como metais pesados, hidrocarbonetos halogenados, pesticidas, fĆ”rmacos, entre outros. Este trabalho pretendeu realizar uma revisĆ£o bibliogrĆ”fica atual sobre a importĆ¢ncia dos biomarcadores na monitorizaĆ§Ć£o ambiental, focando-se nos seguintes aspetos: definiĆ§Ć£o e Ć”reas de aplicabilidade, vantagens e limitaƧƵes, e tipos de biomarcadores: de danificaĆ§Ć£o oxidativa, de neurotoxicidade, de biotransformaĆ§Ć£o, de desregulaĆ§Ć£o endĆ³crina, histopatolĆ³gicos e de genotoxicidade.
The presence of xenobiotic compounds in the environment always poses a risk to its inhabitants and to their habitat. One of the methods used to evaluate the exposure to these compounds and their potential impact on living organisms is through the use of biomarkers. They are able to provide information about the nature of the exposure, effects and individual susceptibility to environmental chemical compounds and are also very useful tools to evaluate and control the long-term damage caused by exposure to xenobiotics, such as heavy metals, halogenated hydrocarbons, pesticides, drugs, among others. This work aimed to perform an up-to-date literature review on the importance of biomarkers in environmental monitoring focused on the following issues: definition and areas of applicability, advantages and limitations, and types of biomarkers: of oxidative damage, neurotoxicity, biotransformation, endocrine disruption, of histological damage, and genotoxicity.
The presence of xenobiotic compounds in the environment always poses a risk to its inhabitants and to their habitat. One of the methods used to evaluate the exposure to these compounds and their potential impact on living organisms is through the use of biomarkers. They are able to provide information about the nature of the exposure, effects and individual susceptibility to environmental chemical compounds and are also very useful tools to evaluate and control the long-term damage caused by exposure to xenobiotics, such as heavy metals, halogenated hydrocarbons, pesticides, drugs, among others. This work aimed to perform an up-to-date literature review on the importance of biomarkers in environmental monitoring focused on the following issues: definition and areas of applicability, advantages and limitations, and types of biomarkers: of oxidative damage, neurotoxicity, biotransformation, endocrine disruption, of histological damage, and genotoxicity.
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Keywords
Biomarcador ambiental Poluente XenobiĆ³tico Biomarcador de exposiĆ§Ć£o Biomarcador de efeito Biomarcador de suscetibilidade Environmental biomarker Pollutant Xenobiotic Biomarker of exposure Biomarker of effect Biomarker of susceptibility