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ProbiĆ³ticos orais

2016-11-07Master thesis Open access
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datacite.subject.fosCiĆŖncias MĆ©dicas::Medicina BĆ”sicapt_PT
dc.contributor.advisorSilva, Ana Catarina
dc.contributor.advisorAbreu, Cristina
dc.contributor.authorGelvez, Yelitza Andreina Jesus
dc.date.accessioned2017-02-15T10:52:22Z
dc.date.available2017-02-15T10:52:22Z
dc.date.issued2016-11-07
dc.description.abstractOs probiĆ³ticos sĆ£o definidos como ā€œmicrorganismos vivos que, quando administrados em quantidades adequadas, conferem benefĆ­cios Ć  saĆŗde do hospedeiroā€. Neste sentido, o uso de probiĆ³ticos tem sido recomendado pelos clĆ­nicos. Entre os diferentes locais do organismo que tĆŖm sido descritos como benĆ©ficos para a aplicaĆ§Ć£o de probiĆ³ticos estĆ” a cavidade oral. EstĆ£o publicados diversos estudos clĆ­nicos que demonstram a diminuiĆ§Ć£o da prevalĆŖncia de inflamaƧƵes gengivais (periodontites), halitose e candidĆ­ases orais em adultos que frequentemente mastigaram gomas contendo probiĆ³ticos. Por outro lado, a diminuiĆ§Ć£o das cĆ”ries dentĆ”rias em crianƧas que consomem regularmente gomas Ć  base de probiĆ³ticos tambĆ©m tem sido referida. A caracterizaĆ§Ć£o das espĆ©cies probiĆ³ticas Ć© fundamental para a obtenĆ§Ć£o de produtos contendo estes microrganismos. Nesse sentido, a anĆ”lise de alguns parĆ¢metros Ć© de extrema importĆ¢ncia, tais como a seguranƧa, eficĆ”cia e a viabilidade das estirpes probiĆ³ticas. Entre os microrganismos mais utilizados em probiĆ³ticos destacam-se as bactĆ©rias dos gĆ©neros Lactobacillus e Bifidobacterium. Os probiĆ³ticos utilizados na terapĆŖutica sĆ£o incorporados em alimentos e formas de dosagem adequadas. Produtos lĆ”cteos e formas farmacĆŖuticas orais sĆ£o exemplos de veĆ­culos utilizados para a dispensa de probiĆ³ticos, tendo as Ćŗltimas demonstrado uma maior eficĆ”cia. Este trabalho tem como objetivo efetuar uma revisĆ£o bibliogrĆ”fica relativa ao estado da arte das diferentes formas farmacĆŖuticas orais Ć  base de probiĆ³ticos, dando exemplos de produtos comercializados.pt_PT
dc.description.abstractProbiotics are defined as ā€œlive microorganisms that when administrated in adequate amounts confer health benefits to the hostā€. In this sense, the use of probiotics has been recommended by physicians. Among the different parts of the body that have been described as beneficial for the application of probiotics is the oral cavity. There are published several clinical studies demonstrating a decrease in the prevalence of gingival inflammation (periodontitis), halitosis and oral candidiasis in adults who often chewed gum containing probiotics. On the other hand, the reduction of dental caries in children who regularly consume chewing gum based on probiotics have also been reported. The characterization of probiotic species is essential to obtain products containing these microorganisms. For this, the analysis of some parameters is very important, such as, safety, effectiveness and viability of probiotic strains. The most widely used probiotic microorganisms include the bacteria Lactobacillus and Bifidobacterium. Probiotics used in therapy are incorporated into suitable dosage forms. Dairy food products and oral dosage forms are examples of vehicles for dispensing probiotics. The latter have shown greater efficacy. This work purpose to make a literature review of the different oral dosage forms based on probiotics, giving examples of products in the market.pt_PT
dc.identifier.tid201651220pt_PT
dc.identifier.urihttp://hdl.handle.net/10284/5819
dc.language.isoporpt_PT
dc.subjectProbiĆ³ticospt_PT
dc.subjectCavidade oralpt_PT
dc.subjectBifidobacteriumpt_PT
dc.subjectLactobacilluspt_PT
dc.subjectProbiĆ³ticos recombinantespt_PT
dc.subjectPeriodontitept_PT
dc.subjectCƔrie dentƔriapt_PT
dc.subjectHalitosept_PT
dc.subjectCandidĆ­ase oralpt_PT
dc.subjectProdutos lƔcteospt_PT
dc.subjectFormas farmacĆŖuticas oraispt_PT
dc.subjectProbioticspt_PT
dc.subjectOral cavitypt_PT
dc.subjectBifidobacteriumpt_PT
dc.subjectLactobacilluspt_PT
dc.subjectRecombinant probioticspt_PT
dc.subjectPeriodontitispt_PT
dc.subjectDental cavitypt_PT
dc.subjectHalitosispt_PT
dc.subjectOral candidiasispt_PT
dc.subjectDairy productspt_PT
dc.subjectOral dosage formspt_PT
dc.titleProbiĆ³ticos oraispt_PT
dc.typemaster thesis
dspace.entity.typePublication
rcaap.rightsopenAccesspt_PT
rcaap.typemasterThesispt_PT
thesis.degree.nameMestrado Integrado em CiĆŖncias FarmacĆŖuticaspt_PT

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