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ProbiĆ³ticos orais
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| PPG_26129 | 1.38 MB | Adobe PDF |
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Abstract(s)
Os probiĆ³ticos sĆ£o definidos como āmicrorganismos vivos que, quando administrados em quantidades adequadas, conferem benefĆcios Ć saĆŗde do hospedeiroā. Neste sentido, o uso de probiĆ³ticos tem sido recomendado pelos clĆnicos.
Entre os diferentes locais do organismo que tĆŖm sido descritos como benĆ©ficos para a aplicaĆ§Ć£o de probiĆ³ticos estĆ” a cavidade oral. EstĆ£o publicados diversos estudos clĆnicos que demonstram a diminuiĆ§Ć£o da prevalĆŖncia de inflamaƧƵes gengivais (periodontites), halitose e candidĆases orais em adultos que frequentemente mastigaram gomas contendo probiĆ³ticos. Por outro lado, a diminuiĆ§Ć£o das cĆ”ries dentĆ”rias em crianƧas que consomem regularmente gomas Ć base de probiĆ³ticos tambĆ©m tem sido referida.
A caracterizaĆ§Ć£o das espĆ©cies probiĆ³ticas Ć© fundamental para a obtenĆ§Ć£o de produtos contendo estes microrganismos. Nesse sentido, a anĆ”lise de alguns parĆ¢metros Ć© de extrema importĆ¢ncia, tais como a seguranƧa, eficĆ”cia e a viabilidade das estirpes probiĆ³ticas. Entre os microrganismos mais utilizados em probiĆ³ticos destacam-se as bactĆ©rias dos gĆ©neros Lactobacillus e Bifidobacterium.
Os probiĆ³ticos utilizados na terapĆŖutica sĆ£o incorporados em alimentos e formas de dosagem adequadas. Produtos lĆ”cteos e formas farmacĆŖuticas orais sĆ£o exemplos de veĆculos utilizados para a dispensa de probiĆ³ticos, tendo as Ćŗltimas demonstrado uma maior eficĆ”cia.
Este trabalho tem como objetivo efetuar uma revisĆ£o bibliogrĆ”fica relativa ao estado da arte das diferentes formas farmacĆŖuticas orais Ć base de probiĆ³ticos, dando exemplos de produtos comercializados.
Probiotics are defined as ālive microorganisms that when administrated in adequate amounts confer health benefits to the hostā. In this sense, the use of probiotics has been recommended by physicians. Among the different parts of the body that have been described as beneficial for the application of probiotics is the oral cavity. There are published several clinical studies demonstrating a decrease in the prevalence of gingival inflammation (periodontitis), halitosis and oral candidiasis in adults who often chewed gum containing probiotics. On the other hand, the reduction of dental caries in children who regularly consume chewing gum based on probiotics have also been reported. The characterization of probiotic species is essential to obtain products containing these microorganisms. For this, the analysis of some parameters is very important, such as, safety, effectiveness and viability of probiotic strains. The most widely used probiotic microorganisms include the bacteria Lactobacillus and Bifidobacterium. Probiotics used in therapy are incorporated into suitable dosage forms. Dairy food products and oral dosage forms are examples of vehicles for dispensing probiotics. The latter have shown greater efficacy. This work purpose to make a literature review of the different oral dosage forms based on probiotics, giving examples of products in the market.
Probiotics are defined as ālive microorganisms that when administrated in adequate amounts confer health benefits to the hostā. In this sense, the use of probiotics has been recommended by physicians. Among the different parts of the body that have been described as beneficial for the application of probiotics is the oral cavity. There are published several clinical studies demonstrating a decrease in the prevalence of gingival inflammation (periodontitis), halitosis and oral candidiasis in adults who often chewed gum containing probiotics. On the other hand, the reduction of dental caries in children who regularly consume chewing gum based on probiotics have also been reported. The characterization of probiotic species is essential to obtain products containing these microorganisms. For this, the analysis of some parameters is very important, such as, safety, effectiveness and viability of probiotic strains. The most widely used probiotic microorganisms include the bacteria Lactobacillus and Bifidobacterium. Probiotics used in therapy are incorporated into suitable dosage forms. Dairy food products and oral dosage forms are examples of vehicles for dispensing probiotics. The latter have shown greater efficacy. This work purpose to make a literature review of the different oral dosage forms based on probiotics, giving examples of products in the market.
Description
Keywords
ProbiĆ³ticos Cavidade oral Bifidobacterium Lactobacillus ProbiĆ³ticos recombinantes Periodontite CĆ”rie dentĆ”ria Halitose CandidĆase oral Produtos lĆ”cteos Formas farmacĆŖuticas orais Probiotics Oral cavity Bifidobacterium Lactobacillus Recombinant probiotics Periodontitis Dental cavity Halitosis Oral candidiasis Dairy products Oral dosage forms