Loading...
Publication
TerapĂȘuticas da COVID-19
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 344.67 KB | Adobe PDF |
Authors
Advisor(s)
Abstract(s)
SARS-CoV-2 Ă© um novo coronavĂrus geneticamente semelhante ao SARS-CoV-1 mas com diferenças estruturais que promovem uma maior taxa de transmissĂŁo. Foi detetado em Wuhan, China, sendo declarado pela Organização Mundial de SaĂșde (OMS) uma pandemia. A sĂndrome respiratĂłria aguda grave, SARS-CoV-2, manifesta-se por sintomas como tosse, febre, dificuldade respiratĂłrias, fadiga ou cefaleias. Esta sĂndrome pode evoluir para doença grave Covid-19 que incide principalmente a nĂvel do trato respiratĂłrio podendo desenvolver pneumonia ou dispneia.
Para o controlo da pandemia, as estratégias utilizadas são medidas de segurança como o distanciamento social, lavagem frequente das mãos e uso de equipamento de proteção.
Relativamente a tratamentos eficazes da COVID-19, ainda nĂŁo hĂĄ uma terapĂȘutica especĂfica desenvolvida, ao que se recorre Ă s terapĂȘuticas primĂĄrias de alĂvio e controlo de sintomas ligeiros, jĂĄ em casos mais severos o uso de alguns medicamentos mostrou se eficaz.
A pressĂŁo da necessidade de uma vacina que cumpra os requisitos de segurança Ă© cada vez maior devido Ă s consequĂȘncias econĂłmicas e de saĂșde global que a pandemia estĂĄ a causar. A uniĂŁo da comunidade cientĂfica foi fulcral para o desenvolvimento da vacina em tempo recorde. De salientar que apesar da rapidez que esta foi desenvolvida, cumpre minuciosamente todos os requisitos solicitados.
Nesta revisĂŁo bibliogrĂĄfica analisou-se vĂĄrios ensaios clĂnicos, tanto de terapĂȘutica medicamentosa para doentes hospitalizados como para o desenvolvimento da vacina, onde se obtiveram resultados bastante satisfatĂłrios a nĂvel de eficĂĄcia e segurança onde se destacou o excelente trabalho por parte das entidades reguladoras e comunidade cientĂfica.
SARS-CoV-2 is a new coronavirus genetically similar to SARS-CoV-1 but with structural differences that promote a higher transmission rate. It was detected in Wuhan, China, and declared a pandemic by the World Health Organization (WHO). Severe acute respiratory syndrome, SARS-CoV-2, presents with symptoms such as cough, fever, difficulty breathing, fatigue or headache. This syndrome can evolve into a severe Covid-19 disease that mainly affects the respiratory tract and may develop pneumonia or dyspnea. To control the pandemic, the strategies used are security measures such as social distancing, frequent hand washing and the use of protective equipment. With regard to effective treatments for COVID-19, there is still no specific therapy developed, using primary therapies to relieve and control mild symptoms. In more severe cases, the use of some medications has proven to be effective. The pressure of the need for a vaccine that meets safety requirements is increasing due to the economic and global health consequences that the pandemic is having. The union of the scientific community was essential for the development of the vaccine in record time. It should be noted that despite the speed that this was developed, it meticulously fulfills all the requested requirements. In this literature review, several clinical trials were analyzed, both for drug therapy for hospitalized patients and for the development of the vaccine, where very satisfactory results were obtained in terms of efficacy and safety, highlighting the excellent work by the regulatory authorities and the scientific community.
SARS-CoV-2 is a new coronavirus genetically similar to SARS-CoV-1 but with structural differences that promote a higher transmission rate. It was detected in Wuhan, China, and declared a pandemic by the World Health Organization (WHO). Severe acute respiratory syndrome, SARS-CoV-2, presents with symptoms such as cough, fever, difficulty breathing, fatigue or headache. This syndrome can evolve into a severe Covid-19 disease that mainly affects the respiratory tract and may develop pneumonia or dyspnea. To control the pandemic, the strategies used are security measures such as social distancing, frequent hand washing and the use of protective equipment. With regard to effective treatments for COVID-19, there is still no specific therapy developed, using primary therapies to relieve and control mild symptoms. In more severe cases, the use of some medications has proven to be effective. The pressure of the need for a vaccine that meets safety requirements is increasing due to the economic and global health consequences that the pandemic is having. The union of the scientific community was essential for the development of the vaccine in record time. It should be noted that despite the speed that this was developed, it meticulously fulfills all the requested requirements. In this literature review, several clinical trials were analyzed, both for drug therapy for hospitalized patients and for the development of the vaccine, where very satisfactory results were obtained in terms of efficacy and safety, highlighting the excellent work by the regulatory authorities and the scientific community.
Description
Keywords
COVID-19 SARS-CoV-2 TerapĂȘutica Therapy