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Covid-19: alternativas terapĂȘuticas e os seus efeitos adversos
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A COVID-19 Ă© uma doença emergente, reportada pela primeira vez em 2019, e responsĂĄvel pela atual pandemia. O objetivo deste trabalho de revisĂŁo bibliogrĂĄfica passa por estudar as alternativas terapĂȘuticas e profilĂĄticas, disponĂveis e promissoras, que podem ser utilizadas no combate ao SARS-CoV-2, assim como os seus efeitos adversos na saĂșde humana.
Muitas abordagens tĂȘm sido propostas, investigadas e usadas pela comunidade cientĂfica para o combate a esta pandemia, incluindo antivirais, antimalĂĄricos, antiparasitĂĄrios, antibiĂłticos, imunoterapia, vacinas, entre outras. Algumas destas opçÔes parecem ter eficĂĄcia e segurança, dependendo do estĂĄgio da doença (estĂĄgio de prevenção, estĂĄgio inicial, estĂĄgio tardio). Contudo, atualmente ainda nĂŁo hĂĄ cura conhecida para a doença COVID-19, mas vĂĄrias abordagens terapĂȘuticas ou profilĂĄticas continuam em fase de desenvolvimento. Por exemplo, a Organização Mundial de SaĂșde prossegue a realização de ensaios clĂnicos de medicamentos, jĂĄ usados para outras doenças, para tratar a covid-19.
Embora a vacinação, amplamente distribuĂda nos paĂses mais ricos, pareça ser uma arma segura e eficaz para controlar esta doença, Ă© essencial tornĂĄ-la igualmente acessĂvel a paĂses de renda baixa / mĂ©dia. A economia Ă© um fator importante a ter em conta na situação atual, decisivo para garantir que, a nĂvel global, nĂŁo deve haver falta de profilaxia nem tratamento, de forma a que todos os esforços sejam feitos para controlar a COVID-19.
COVID-19 is an emerging disease, first reported in 2019, and responsible for the current pandemic. The aim of this bibliographic review work is to study the available and promising therapeutic and prophylactic alternatives that can be used to combat SARS-CoV-2, as well as its adverse effects on human health. Many approaches have been proposed, investigated and used by the scientific community to fight this pandemic, including antivirals, antimalarials, antiparasitics, antibiotics, immunotherapy, vaccines, among others. Some of these options appear to have efficacy and safety depending on the stage of the disease (prevention stage, early stage, late stage). However, there is currently no known cure for COVID-19 disease, but several therapeutic or prophylactic approaches are still under development. For example, the World Health Organization continues to carry out clinical trials of drugs, already used for other diseases, to treat covid-19. Although vaccination, widely distributed in richer countries, appears to be a safe and effective weapon to control this disease, it is essential to make it equally accessible to low/middle income countries. Economy is an important factor to take into account in the current situation, decisive to ensure that, globally, there should be no lack of prophylaxis or treatment, so that every effort is made to control COVID-19.
COVID-19 is an emerging disease, first reported in 2019, and responsible for the current pandemic. The aim of this bibliographic review work is to study the available and promising therapeutic and prophylactic alternatives that can be used to combat SARS-CoV-2, as well as its adverse effects on human health. Many approaches have been proposed, investigated and used by the scientific community to fight this pandemic, including antivirals, antimalarials, antiparasitics, antibiotics, immunotherapy, vaccines, among others. Some of these options appear to have efficacy and safety depending on the stage of the disease (prevention stage, early stage, late stage). However, there is currently no known cure for COVID-19 disease, but several therapeutic or prophylactic approaches are still under development. For example, the World Health Organization continues to carry out clinical trials of drugs, already used for other diseases, to treat covid-19. Although vaccination, widely distributed in richer countries, appears to be a safe and effective weapon to control this disease, it is essential to make it equally accessible to low/middle income countries. Economy is an important factor to take into account in the current situation, decisive to ensure that, globally, there should be no lack of prophylaxis or treatment, so that every effort is made to control COVID-19.
Description
Keywords
Alternativas terapĂȘuticas Profilaxia Covid-19 SARS-CoV-2 Efeitos adversos Therapeutic alternatives Prophylaxis Adverse effects