Loading...
Publication
Lúpus eritematoso sistémico e patologia orofacial: um caso clínico
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| Projeto de pós-graduação_39213 | 1.91 MB | Adobe PDF |
Authors
Advisor(s)
Abstract(s)
Algumas doenças de origem autoimune frequentemente têm um impacto significativo na cavidade oral, manifestando-se de várias formas clínicas que podem dificultar o diagnóstico preciso e a gestão adequada destas condições. O lúpus eritematoso sistémico (LES) é um exemplo de uma doença autoimune crónica que afeta a cavidade oral e é, também, conhecida pela sua complexidade clínica. É uma patologia de origem multifatorial e que apresenta uma elevada prevalência entre mulheres em idade fértil, com o início geralmente ocorrendo entre os 15 e 50 anos de idade. Esta doença pode comprometer qualquer órgão do corpo, incluindo articulações, pele, pulmões, coração, sistema nervoso, vasos sanguíneos e fígado. Clinicamente, o LES caracteriza-se por um padrão de apresentação que inclui episódios alternados de exacerbação e remissão dos sintomas. Esta revisão tem como objetivo fornecer uma visão geral das manifestações orais associadas ao LES, a sua prevalência, patogénese, diagnóstico e opções de tratamento. Além disso, foi apresentado um caso clínico de uma paciente do género feminino de 50 anos diagnosticada com LES em 2012, tendo sido observado e documentado as manifestações orais. Pacientes com LES reportam frequentemente úlceras, xerostomia e gengivite. Também enfrentam um risco elevado de outros problemas dentários, como cáries e doenças periodontais, o que está associado não só ao uso contínuo de imunossupressores, mas também à idade em que a doença se manifestou pela primeira vez. A revisão evidencia que a presença de manifestações orais é comum e frequentemente relacionada com a duração da doença e o tratamento, sublinhando a necessidade de uma vigilância regular e um tratamento especializado para minimizar o impacto destas complicações. Devido à complexidade e à variedade das manifestações clínicas do LES, é crucial adotar uma abordagem multidisciplinar, que envolva tanto o tratamento médico especializado como a atenção dentária apropriada, para garantir uma gestão eficaz da doença e melhorar a qualidade de vida dos pacientes.
Some autoimmune diseases often have a significant impact on the oral cavity, manifesting in various clinical forms that can hinder the accurate diagnosis and proper management of these conditions. Systemic lupus erythematosus (SLE) is an example of a chronic autoimmune disease that affects the oral cavity and is also known for its clinical complexity. It is a multifactorial pathology with a high prevalence among women of childbearing age, typically beginning between the ages of 15 and 50. This disease can affect any organ in the body, including joints, skin, lungs, heart, nervous system, blood vessels, and liver. Clinically, SLE is characterized by a pattern of alternating episodes of symptom exacerbation and remission. This review aims to provide an overview of the oral manifestations associated with SLE, their prevalence, pathogenesis, diagnosis, and treatment options. Additionally, a clinical case of a 50-year-old female patient diagnosed with SLE in 2012 was presented, with the oral manifestations observed and documented. Patients with SLE often report ulcers, xerostomia, and gingivitis. They also face a high risk of other dental problems such as caries and periodontal diseases, which is associated not only with the continuous use of immunosuppressants but also with the age at which the disease first manifested. The review highlights that the presence of oral manifestations is common and often related to the duration of the disease and treatment, emphasizing the need for regular monitoring and specialized treatment to minimize the impact of these complications. Due to the complexity and variety of SLE clinical manifestations, it is crucial to adopt a multidisciplinary approach that involves both specialized medical treatment and appropriate dental care to ensure effective disease management and improve the quality of life of these patients.
Some autoimmune diseases often have a significant impact on the oral cavity, manifesting in various clinical forms that can hinder the accurate diagnosis and proper management of these conditions. Systemic lupus erythematosus (SLE) is an example of a chronic autoimmune disease that affects the oral cavity and is also known for its clinical complexity. It is a multifactorial pathology with a high prevalence among women of childbearing age, typically beginning between the ages of 15 and 50. This disease can affect any organ in the body, including joints, skin, lungs, heart, nervous system, blood vessels, and liver. Clinically, SLE is characterized by a pattern of alternating episodes of symptom exacerbation and remission. This review aims to provide an overview of the oral manifestations associated with SLE, their prevalence, pathogenesis, diagnosis, and treatment options. Additionally, a clinical case of a 50-year-old female patient diagnosed with SLE in 2012 was presented, with the oral manifestations observed and documented. Patients with SLE often report ulcers, xerostomia, and gingivitis. They also face a high risk of other dental problems such as caries and periodontal diseases, which is associated not only with the continuous use of immunosuppressants but also with the age at which the disease first manifested. The review highlights that the presence of oral manifestations is common and often related to the duration of the disease and treatment, emphasizing the need for regular monitoring and specialized treatment to minimize the impact of these complications. Due to the complexity and variety of SLE clinical manifestations, it is crucial to adopt a multidisciplinary approach that involves both specialized medical treatment and appropriate dental care to ensure effective disease management and improve the quality of life of these patients.
Description
Keywords
Lúpus eritematoso sistémico Manifestações orais Patologia orofacial Systemic lupus erythematosus Oral manifestations Orofacial pathology