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A importância da saliva como biópsia líquida no cancro oral
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| PPG_38799 | 256.44 KB | Adobe PDF |
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Abstract(s)
O presente trabalho consta em uma revisão bibliográfica que tem como objetivo principal analisar a importância da saliva como material para biópsias líquidas e a sua relação com a possível deteção precoce e controle do cancro, afim de buscar tratamentos mais rápidos e terapêuticas mais eficazes. As biópsias líquidas e a saliva são uma combinação altamente harmoniosa, pois por apresentarem diversas vantagens, e a saliva, por ser um material de fácil acesso e não invasivo, têm vindo a ser descritas de forma crescente para deteção de diferentes tipos de neoplasias, e entre elas, o cancro oral. O que por si só ilustra o enorme potencial da introdução das biópsias líquidas na prática clínica. Nessa revisão, vários estudos com diferentes tipos de biomarcadores foram analisados e comparados, para poder investigar a associação destes com a tumorigéne. O campo de pesquisa das biópsias líquidas é bastante novo e mais estudos comparativos precisam ser realizados para consolidar respostas mais precisas.
The present work consists of a bibliographic review that has as main objective to analyze the importance of saliva as a material for liquid biopsies and its relationship with the possible early detection and control of cancer, in order to seek faster and more effective therapeutic treatments. Liquid biopsies and saliva are a highly harmonious combination because they have several advantages, and saliva, being an easily accessible and non-invasive material, has been increasingly described for different types of neoplasms and, among them, oral cancer. Which in itself illustrates the enormous potential of introducing liquid biopsies into clinical practice. In this review, several studies with different types of biomarkers were analyzed and compared in order to investigate their association with tumorigen. The field of research on liquid biopsies is quite new and more comparative studies need to be done to consolidate more accurate answers.
The present work consists of a bibliographic review that has as main objective to analyze the importance of saliva as a material for liquid biopsies and its relationship with the possible early detection and control of cancer, in order to seek faster and more effective therapeutic treatments. Liquid biopsies and saliva are a highly harmonious combination because they have several advantages, and saliva, being an easily accessible and non-invasive material, has been increasingly described for different types of neoplasms and, among them, oral cancer. Which in itself illustrates the enormous potential of introducing liquid biopsies into clinical practice. In this review, several studies with different types of biomarkers were analyzed and compared in order to investigate their association with tumorigen. The field of research on liquid biopsies is quite new and more comparative studies need to be done to consolidate more accurate answers.
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Keywords
Biópsias líquidas Biomarcadores salivares Exossomas Cancêr oral Liquid biopsy Salivary biomarkers Exossomes Oral cancer