| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| PPG_25685 | 1.13 MB | Adobe PDF |
Authors
Advisor(s)
Abstract(s)
Os biomateriais podem ser utilizados para substituir, no todo ou em parte, sistemas biológicos quando estes são impossibilitados de cumprir as suas funções naturais.
Atualmente existe uma panóplia de biomateriais que podem ser divididos, de acordo com a sua origem, em materiais naturais e sintéticos. O quitosano consiste num biomaterial natural, hidrófilo, atóxico, biodegradável e biocompatível, produzido por fontes naturais renováveis, cujas propriedades vêm sendo exploradas em aplicações industriais e tecnológicas desde há vários anos.
O quitosano é um dos biomateriais com maior potencial de utilização na medicina regenerativa. Desde fios de suturas, a biomateriais de aplicação na pele, osso e cartilagens, o quitosano possui uma panóplia de possibilidades de utilização neste campo.
O objetivo deste trabalho de revisão bibliográfica é evidenciar os avanços do quitosano e sua vasta aplicabilidade como biomaterial. A composição do tecido ósseo, tecido cartilaginoso, e a pele, bem como o conceito de biomaterial e quitina serão abordados nas diferentes secções. Por fim, é efetuada uma referência relativa às técnicas de engenharia de tecidos com recurso ao quitosano como, bem como uma avaliação crítica do seu potencial de sucesso, através de exemplos práticos relativos aos seus avanços recentes.
Biomaterials can be used to replace, in whole or in part, biological systems when they are unable to comply with its natural functions. Currently there is a range of biomaterials that can be divided, according to its origin, in natural and synthetic materials. Chitosan is a natural biomaterial, hydrophilic, non-toxic, biodegradable and biocompatible, produced from renewable natural sources, whose properties have been explored in industrial and technological applications for several years. Chitosan is one of the biomaterials with potential for use in regenerative medicine. Since sutures, up to application of biomaterials in the skin, bone and cartilage, the chitosan has a range of potential uses in this field. The objective of this literature review is to highlight the progress of chitosan and his extensive applicability as a biomaterial. The composition of bone, cartilage, and skin, as well as the concept of biomaterial and chitin are discussed in different sections. Finally, a reference on of tissue engineering techniques using chitosan, as well as a critical evaluation of their potential for success through practical examples relating to its recent advances.
Biomaterials can be used to replace, in whole or in part, biological systems when they are unable to comply with its natural functions. Currently there is a range of biomaterials that can be divided, according to its origin, in natural and synthetic materials. Chitosan is a natural biomaterial, hydrophilic, non-toxic, biodegradable and biocompatible, produced from renewable natural sources, whose properties have been explored in industrial and technological applications for several years. Chitosan is one of the biomaterials with potential for use in regenerative medicine. Since sutures, up to application of biomaterials in the skin, bone and cartilage, the chitosan has a range of potential uses in this field. The objective of this literature review is to highlight the progress of chitosan and his extensive applicability as a biomaterial. The composition of bone, cartilage, and skin, as well as the concept of biomaterial and chitin are discussed in different sections. Finally, a reference on of tissue engineering techniques using chitosan, as well as a critical evaluation of their potential for success through practical examples relating to its recent advances.
Description
Keywords
Quitosano Quitina Biomaterial Propriedades do quitosano Engenharia de tecidos Chitosan Chitin Biomaterial Chitosan properties Tissue Engineering
