Loading...
Publication
Potencial antimicrobiano dos canabinóides
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| Projeto de pós-graduação_38405 | 701.49 KB | Adobe PDF |
Advisor(s)
Abstract(s)
No cenário de combate à resistência bacteriana aos antibióticos, muitas substâncias têm sido investigadas quanto à sua potencial atividade antibacteriana, incluindo substâncias provenientes de produtos naturais. Os canabinóides têm sido associados a múltiplas e potenciais atividades biológicas, com destaque para as suas propriedades ansiolíticas e antipsicóticas, anti-inflamatórias, analgésicas, antioxidantes e neuroprotetoras. Estes compostos poderão ser utilizados no tratamento de infeções microbianas, potenciando o efeito dos fármacos normalmente utilizados.
A investigação relativamente ao potencial antimicrobiano dos canabinóides forneceu conhecimentos importantes sobre a sua eficácia contra microrganismos resistentes a medicamentos, embora o seu uso seja controverso. No entanto, ainda é necessário realizar mais pesquisas e estudos clínicos para fundamentar a sua aplicação terapêutica.
Desta forma, neste trabalho, foi possível verificar que os canabinóides apresentam potencial antimicrobiano contra alguns microrganismos e também que o uso de canabinóides conjugados com tratamentos convencionais pode conduzir a um efeito sinérgico.
In the scenario of combating bacterial resistance to antibiotics, many substances have been investigated for their potential antibacterial activity, including substances from natural products. Cannabinoids have been associated with multiple and potential biological activities, with emphasis on their anxiolytic and antipsychotic, anti-inflammatory, analgesic, antioxidant, and neuroprotective properties. These compounds may be used in the treatment of microbial infections, enhancing the effect of commonly used drugs. The research into the antimicrobial potential of cannabinoids has provided important insights into their effectiveness against drug-resistant microorganisms, although their use is controversial. However, more research and clinical studies still need to be carried out to substantiate their therapeutic application. Thus, in this work, it was possible to verify that cannabinoids have antimicrobial potential against some microorganisms and also that the use of cannabinoids combined with conventional treatments can lead to a synergistic effect.
In the scenario of combating bacterial resistance to antibiotics, many substances have been investigated for their potential antibacterial activity, including substances from natural products. Cannabinoids have been associated with multiple and potential biological activities, with emphasis on their anxiolytic and antipsychotic, anti-inflammatory, analgesic, antioxidant, and neuroprotective properties. These compounds may be used in the treatment of microbial infections, enhancing the effect of commonly used drugs. The research into the antimicrobial potential of cannabinoids has provided important insights into their effectiveness against drug-resistant microorganisms, although their use is controversial. However, more research and clinical studies still need to be carried out to substantiate their therapeutic application. Thus, in this work, it was possible to verify that cannabinoids have antimicrobial potential against some microorganisms and also that the use of cannabinoids combined with conventional treatments can lead to a synergistic effect.
Description
Keywords
Canabinóides Canábis Potencial antimicrobiano Antibacteriano Antiviral SARS-CoV-2 COVID-19 Cannabinoids Cannabis Antimicrobial potential Antibacterial Antiviral