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Eficácia da ventilação não invasiva em jovens adultos com distrofia muscular de Duchenne: revisão bibliográfica
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Abstract(s)
Objetivo: Verificar a eficácia da ventilação não invasiva (VNI) na distrofia muscular de Duchenne (DMD). Metodologia: Foi realizada uma pesquisa computorizada entre dezembro de 2019 e janeiro de 2020 nas bases de dados Pubmed e Web of Science usando a estratégia de pesquisa de palavras-chave. Os artigos foram todos avaliados usando a Escala Critical Appraisal Skills Programme. Resultados: Nesta revisão foram incluídos onze artigos no total, verificando-se que a insuflação por pressão positiva reduz a carga nos músculos respiratórios, não havendo aumento da capacidade vital (CV), e lentifica o declínio da função pulmonar. A insuflação-exsuflação mecânica do Cough assist permitiu a remoção de microatelectasias, assim como o aumento de compliance e CV. Além disso, constatou-se que a VNI melhora a fraqueza muscular respiratória e os parâmetros respiratórios. Conclusão: A VNI parece ser uma técnica benéfica na DMD, reduzindo o trabalho dos músculos respiratórios, melhora a função pulmonar, prolonga a vida e evita a traqueostomia.
Objective: To verify non-invasive ventilation in Duchenne muscular dystrophy. Methodology: Computerized research was carried out between December 2019 and January 2020 in the Pubmed and Web Science databases using the keyword search strategy. All the articles were evaluated using the Critical Appraisal Skills Programme Scale. Results: Eleven articles were included in this review, verifying that positive pressure insufflation reduces the load on the respiratory muscles, with no increase in vital capacity, and slows down the decline in lung function. The mechanical insufflation-exsufflation of Cough assist allowed the removal of microatelectasis, as well as increased compliance and vital capacity. In addition, it was found that non-invasive ventilation improves respiratory muscle weakness and respiratory parameters. Conclusion: Non-invasive ventilation appears to be a beneficial technique in these patients, reducing the work of the respiratory muscles, improving lung function, prolonging life and avoiding tracheostomy.
Objective: To verify non-invasive ventilation in Duchenne muscular dystrophy. Methodology: Computerized research was carried out between December 2019 and January 2020 in the Pubmed and Web Science databases using the keyword search strategy. All the articles were evaluated using the Critical Appraisal Skills Programme Scale. Results: Eleven articles were included in this review, verifying that positive pressure insufflation reduces the load on the respiratory muscles, with no increase in vital capacity, and slows down the decline in lung function. The mechanical insufflation-exsufflation of Cough assist allowed the removal of microatelectasis, as well as increased compliance and vital capacity. In addition, it was found that non-invasive ventilation improves respiratory muscle weakness and respiratory parameters. Conclusion: Non-invasive ventilation appears to be a beneficial technique in these patients, reducing the work of the respiratory muscles, improving lung function, prolonging life and avoiding tracheostomy.
Description
Projeto de Graduação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciada em Fisioterapia
Keywords
Doenças neuromusculares Duchenne Falência respiratória Função pulmonar Mecânica insuflação-exsuflação Ventilação não invasiva Duchenne Mechanical insufflation-exsufflation Neuromuscular diseases Non invasive ventilation Pulmonary function Respiratory failure