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PrevalĂȘncia de Staphylococcus spp na cavidade bucal e seu impacto clĂ­nico

2018-07-23Master thesis Open access
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datacite.subject.fosCiĂȘncias MĂ©dicas::Medicina ClĂ­nicapt_PT
dc.contributor.advisorMagalhĂŁes, Ricardo
dc.contributor.authorLoberto, Jussara Cia Sanches
dc.date.accessioned2019-02-04T15:31:03Z
dc.date.available2019-02-04T15:31:03Z
dc.date.issued2018-07-23
dc.description.abstractOs Staphylococcus aureus sĂŁo importantes patĂłgenos, responsĂĄveis por diversas infeçÔes sistĂȘmicas, como bacteriemia e endocardite. A origem dessas infecçÔes pode ser do biofilme bucal, onde os microorganismos se tornam menos sensĂ­veis aos antibiĂłticos. Os S. aureus sĂŁo resistentes a vĂĄrios antibiĂłticos e resultam em tratamentos complicados. O objetivo deste estudo foi verificar, a prevalĂȘncia de Staphylococcus spp na cavidade bucal, seu impacto clĂ­nico na etiologia das infecçÔes orais e sistĂȘmicas e seu comportamento frente aos antibiĂłticos mais prescritos pelos dentistas. A literatura mostrou que os Staphylococcus spp foram bastante prevalentes na cavidade bucal. A amoxicilina foi o antibiĂłtico mais prescrito, no entanto, na presença de Staphylococcus aureus apresenta uma eficĂĄcia reduzida. A associação com o ĂĄcido clavulĂąnico pode ter efeito contra algumas estirpes, mas nĂŁo para as estirpes resistentes Ă  meticilina. E se estas forem para a corrente sanguĂ­nea, poderia evoluir para uma endocardite de difĂ­cil tratamento.pt_PT
dc.description.abstractS. aureus is an important pathogen, responsible for several systemic infections, such as bacteremia and endocarditis. The origin of these infections can be from oral biofilm, where microorganisms become less sensitive to the antibiotics. S. aureus is quite resistant to several antibiotics. The objective of this study was to verify the prevalence of Staphylococcus spp in the oral cavity, its clinical impact in the aetiology of oral and systemic infections, as well as to investigate the behaviour of these microorganisms in relation to the antibiotics most prescribed by dentists. Literature suggest that Staphylococci spp are very prevalent in the oral cavity. Amoxicillin was the most prescribed antibiotic, however, in the presence of Staphylococcus aureus it has a reduced efficacy. The association with clavulanic acid may have some effect against some strains, but not for the strains resistant to methicillin., and when into the bloodstream, it could progress to difficult-to-treat endocarditis.pt_PT
dc.identifier.tid202684814
dc.identifier.urihttp://hdl.handle.net/10284/7269
dc.language.isoporpt_PT
dc.subjectPrevalĂȘnciapt_PT
dc.subjectStaphylococcus spppt_PT
dc.subjectS. aureuspt_PT
dc.subjectCavidade oralpt_PT
dc.subjectAntibiĂłticospt_PT
dc.subjectPrescriçãopt_PT
dc.subjectPrevalencept_PT
dc.subjectOral cavitypt_PT
dc.subjectAntibioticspt_PT
dc.subjectPrescriptionpt_PT
dc.titlePrevalĂȘncia de Staphylococcus spp na cavidade bucal e seu impacto clĂ­nicopt_PT
dc.typemaster thesis
dspace.entity.typePublication
rcaap.rightsopenAccesspt_PT
rcaap.typemasterThesispt_PT
thesis.degree.nameMestrado Integrado em Medicina DentĂĄriapt_PT

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