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PrevalĂȘncia de Staphylococcus spp na cavidade bucal e seu impacto clĂnico
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Os Staphylococcus aureus sĂŁo importantes patĂłgenos, responsĂĄveis por diversas infeçÔes sistĂȘmicas, como bacteriemia e endocardite. A origem dessas infecçÔes pode ser do biofilme bucal, onde os microorganismos se tornam menos sensĂveis aos antibiĂłticos. Os S. aureus sĂŁo resistentes a vĂĄrios antibiĂłticos e resultam em tratamentos complicados. O objetivo deste estudo foi verificar, a prevalĂȘncia de Staphylococcus spp na cavidade bucal, seu impacto clĂnico na etiologia das infecçÔes orais e sistĂȘmicas e seu comportamento frente aos antibiĂłticos mais prescritos pelos dentistas. A literatura mostrou que os Staphylococcus spp foram bastante prevalentes na cavidade bucal. A amoxicilina foi o antibiĂłtico mais prescrito, no entanto, na presença de Staphylococcus aureus apresenta uma eficĂĄcia reduzida. A associação com o ĂĄcido clavulĂąnico pode ter efeito contra algumas estirpes, mas nĂŁo para as estirpes resistentes Ă meticilina. E se estas forem para a corrente sanguĂnea, poderia evoluir para uma endocardite de difĂcil tratamento.
S. aureus is an important pathogen, responsible for several systemic infections, such as bacteremia and endocarditis. The origin of these infections can be from oral biofilm, where microorganisms become less sensitive to the antibiotics. S. aureus is quite resistant to several antibiotics. The objective of this study was to verify the prevalence of Staphylococcus spp in the oral cavity, its clinical impact in the aetiology of oral and systemic infections, as well as to investigate the behaviour of these microorganisms in relation to the antibiotics most prescribed by dentists. Literature suggest that Staphylococci spp are very prevalent in the oral cavity. Amoxicillin was the most prescribed antibiotic, however, in the presence of Staphylococcus aureus it has a reduced efficacy. The association with clavulanic acid may have some effect against some strains, but not for the strains resistant to methicillin., and when into the bloodstream, it could progress to difficult-to-treat endocarditis.
S. aureus is an important pathogen, responsible for several systemic infections, such as bacteremia and endocarditis. The origin of these infections can be from oral biofilm, where microorganisms become less sensitive to the antibiotics. S. aureus is quite resistant to several antibiotics. The objective of this study was to verify the prevalence of Staphylococcus spp in the oral cavity, its clinical impact in the aetiology of oral and systemic infections, as well as to investigate the behaviour of these microorganisms in relation to the antibiotics most prescribed by dentists. Literature suggest that Staphylococci spp are very prevalent in the oral cavity. Amoxicillin was the most prescribed antibiotic, however, in the presence of Staphylococcus aureus it has a reduced efficacy. The association with clavulanic acid may have some effect against some strains, but not for the strains resistant to methicillin., and when into the bloodstream, it could progress to difficult-to-treat endocarditis.
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Keywords
PrevalĂȘncia Staphylococcus spp S. aureus Cavidade oral AntibiĂłticos Prescrição Prevalence Oral cavity Antibiotics Prescription