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Publication
Sono e cancro da mama
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| PPG_30506 | 501.28 KB | Adobe PDF |
Advisor(s)
Abstract(s)
Objetivos: O objetivo deste projeto foi analisar as bases fisiológicas do sono e do cancro e verificar a associação entre os distúrbios de sono e a incidência de cancro, especificamente o cancro da mama.
Métodos: A metodologia, de cariz teórico, teve por base as publicações científicas pesquisadas na Língua Portuguesa, Língua Inglesa e Língua Espanhola, a partir de 2005 até ao término da redação da tese. A pesquisa via on-line foi realizada através de bases científicas na área do sono e do cancro. Foram selecionadas as publicações consideradas importantes para o tema, através da pesquisa por palavras-chaves diretamente relacionadas com o sono e o cancro.
Descrição: Os distúrbios do sono, isto é, o défice de sono, quer em duração, quer em qualidade, podem estar associados a riscos aumentados de diversas patologias, nomeadamente a obesidade, a diabetes, alguns cancros, entre outros. A causa parece estar relacionada a alterações no sistema neuro-endócrino com resultados negativos para o sistema imunológico e o metabolismo. Até à data, o número de estudos publicados sobre a duração do sono e o risco de cancro produziram resultados interessantes, porém inconsistentes, relatando riscos elevados associados com durações de sono em períodos curtos e longos, bem como sem qualquer associação para uma variedade de cancros. Essas inconsistências podem ser parcialmente reflexo de diferentes caminhos mecanicistas que operam para diferentes sítios de cancro.
A incidência de cancro da mama aumentou nas últimas décadas por razões que são parcialmente compreendidas. As perturbações do sono são dos sintomas mais frequentes entre pacientes oncológicos, especialmente em doentes com cancro da mama.
Objectives: The objective of this project was to analyze the physiological bases of sleep and cancer and to verify the association between sleep disorders and the incidence of cancer, specifically breast cancer. Methods: The theoretical methodology was based on the scientific publications researched in the Portuguese Language, English Language and Spanish Language, from 2005 until the end of the writing of the thesis. Online research was conducted through scientific bases in the area of sleep and cancer. We selected the publications considered important for the theme, through the search for keywords directly related to sleep and cancer. Description: Sleep disturbances, that is, sleep deficit, both in duration and in quality, may be associated with increased risks of several pathologies, namely obesity, diabetes, some cancers, among others. The cause seems to be related to changes in the neuro-endocrine system with negative results for the immune system and metabolism. To date, the number of published studies on sleep duration and cancer risk have yielded interesting yet inconsistent results, reporting high risks associated with short and long duration of sleep as well as no association for a variety of cancers. These inconsistencies may be partially reflective of different mechanistic pathways that operate for different cancer sites. The incidence of breast cancer has increased in recent decades for reasons that are partially understood. Sleep disturbances are among the most common symptoms among oncology patients, especially in patients with breast cancer.
Objectives: The objective of this project was to analyze the physiological bases of sleep and cancer and to verify the association between sleep disorders and the incidence of cancer, specifically breast cancer. Methods: The theoretical methodology was based on the scientific publications researched in the Portuguese Language, English Language and Spanish Language, from 2005 until the end of the writing of the thesis. Online research was conducted through scientific bases in the area of sleep and cancer. We selected the publications considered important for the theme, through the search for keywords directly related to sleep and cancer. Description: Sleep disturbances, that is, sleep deficit, both in duration and in quality, may be associated with increased risks of several pathologies, namely obesity, diabetes, some cancers, among others. The cause seems to be related to changes in the neuro-endocrine system with negative results for the immune system and metabolism. To date, the number of published studies on sleep duration and cancer risk have yielded interesting yet inconsistent results, reporting high risks associated with short and long duration of sleep as well as no association for a variety of cancers. These inconsistencies may be partially reflective of different mechanistic pathways that operate for different cancer sites. The incidence of breast cancer has increased in recent decades for reasons that are partially understood. Sleep disturbances are among the most common symptoms among oncology patients, especially in patients with breast cancer.
Description
Keywords
Sono Distúrbios do sono Insónias Fatores de risco Cancro da mama Sleep Sleep disorders Insomnia Risk factors Breast cancer