ESSFP - Artigos em Revistas Científicas Internacionais com Arbitragem Científica
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- Cancer nanopharmaceuticals: physicochemical characterization and in vitro/in vivo applicationsPublication . Zielińska, Aleksandra; Szalata, Marlena; Gorczyński, Adam; Karczewski, Jacek; Eder, Piotr; Severino, Patrícia; Cabeda, JM; Souto, Eliana B.; Słomski, RyszardPhysicochemical, pharmacokinetic, and biopharmaceutical characterization tools play a key role in the assessment of nanopharmaceuticals’ potential imaging analysis and for site-specific delivery of anti-cancers to neoplastic cells/tissues. If diagnostic tools and therapeutic approaches are combined in one single nanoparticle, a new platform called nanotheragnostics is generated. Several analytical technologies allow us to characterize nanopharmaceuticals and nanoparticles and their properties so that they can be properly used in cancer therapy. This paper describes the role of multifunctional nanoparticles in cancer diagnosis and treatment, describing how nanotheragnostics can be useful in modern chemotherapy, and finally, the challenges associated with the commercialization of nanoparticles for cancer therapy.
- Climate anxiety: trigger or threat for mental disorders?Publication . Sampaio, Francisco; Sequeira, Carlos
- Development and psychometric properties of the Therapeutic Relationship Assessment Scale‐NursePublication . Ferreira Coelho, Joana Catarina; Sampaio, Francisco; Nogueira, Maria José Carvalho; Sequeira, Carlos; Lleixá-Fortuño, Mar; Roldan-Merino, JuanIntroduction: The therapeutic relationship (TR) is essential to providing psychiatric and mental health nursing care. Nevertheless, no assessment tools exclusive for assessing nursing TR were found in the literature. Aim: To describe and evaluate the psychometric properties (reliability and construct validity) of a scale that allows assessing the quality of TR established between the nurse and the patient. Method: A survey method was adopted, using a convenience sample of 356 mental health nurses. Internal consistency was assessed by Cronbach's alpha and Omega index. Results: A total of 221 mental health nurses participated in the study (response rate = 62.08%). The scale's final structure has 25 items. Cronbach's alpha was 0.93, ranging from 0.78 to 0.88 for each of the factors. The cumulative variance explained in a four-factor structure was 71.12%. Discussion: The Therapeutic Relationship Assessment Scale (TRAS)-Nurse presents good psychometric properties. In the light of Benner's theory, it can be an useful tool for novice nurses to better understand what aspects they should pay attention to for establishing a successful TR. Implications for Practice: Mental health nurses can use the TRAS-Nurse, thus having a scale available that allows them to self-assess the quality of TR they establish with their patients.
- Development of a clinical data model addressing the nursing focus “anxiety”: a consensus development studyPublication . Sampaio, Francisco; Gonçalves, Patrícia; P., Vieira-Marques; Sequeira, Carlos; Lluch-Canut, TeresaAnxiety disorders are among the most prevalent mental disorders worldwide. However, anxiety is not exclusive to anxiety disorders. In fact, the nursing discipline approaches anxiety as a human response to health conditions/life processes. Health information systems should primarily contribute to improving the quality of care, patient safety, and the effectiveness of care delivery. Nevertheless, nursing information systems still fail to incorporate evidence-based clinical data models addressing the nursing focus “anxiety.” Thus, this study aimed to obtain consensus on the data to be included in a clinical data model addressing the nursing focus “anxiety,” its organization, and its interrelationships by using a brainstorming session and a modified e-Delphi technique with a panel of nurse experts from across Portugal. Eight experts participated in the brainstorming session. A total of 59 and 54 participants completed the survey in e-Delphi rounds 1 and 2, respectively. Consensus was achieved to all data presented to the participants, and these data were later included in the clinical data model. This evidence-based clinical data model, grounded on a nursing theory and with standardized nursing language, will substantially contribute to nursing documentation and, consequently, to nursing care targeted at patients with anxiety.
- Editorial: Mental health literacy: how to obtain and maintain positive mental healthPublication . Sequeira, Carlos; Sampaio, Francisco; Pinho, Lara Guedes de; Araújo, Odete; Lluch-Canut, Teresa; Sousa, Lia
- Enfermeiros de atenção primária à saúde: atitudes frente à pessoa com transtorno mentalPublication . Nobrega, Maria Do Perpétuo Socorro De Sousa; Fernandes, Carla Sílvia; Zerbetto, Sonia; Sampaio, Francisco; Carvalho, J.C.; Cristina De Sousa Chaves, SuellenObjetivo: Identificar as atitudes dos enfermeiros que atuam na Atenção Primária à Saúde frente à pessoa com transtorno mental e as variáveis relacionados aos cuidados de saúde prestados. Metodologia: Estudo descritivo, correlacional, com 250 enfermeiros de 69 Unidades Básica de Saúde do município de São Paulo. A coleta de dados ocorreu entre abril e agosto de 2019 por meio da escala “Opiniões acerca da Doença Mental”. Os dados foram analisados por meio do teste de KrusKal-Wallis, com nível de confiança de 95% e significância estatística de p<0,05. Resultados: A média global da escala foi 197, que demonstra atitudes negativas especialmente nas dimensões de Autoritarismo (44,6), Restrição Social (42,0), e positiva na dimensão Benevolência (51,7). Conclusão: Os enfermeiros apresentam, tendencialmente, perfil atitudinal estigmatizante. É necessária intervenção formativa e permanente para que seja possível reduzir o estigma e melhorar o cuidado de base comunitária preconizado nas diretrizes da Rede de Atenção Psicossocial.
- Gender differences in mental health, academic life satisfaction and psychological vulnerability in a sample of college freshmen: a cross-sectional studyPublication . Nogueira, Maria; Sequeira, Carlos; Sampaio, FranciscoGender differences among undergraduates are mainly found in the prevalence of common mental disorders such as depression, anxiety, somatic complaints, and sexual violence. However, there is a lack of information in the literature about gender differences in academic life satisfaction and psychological vulnerability among freshmen. Thus, this study aimed to identify gender differences in demographics, mental health, academic life satisfaction, and psychological vulnerability of freshmen. A cross-sectional study was conducted on a sample of 560 Portuguese freshmen. An online survey was used to collect data in all 29 Lisbon District colleges. Data were collected through a demographic and academic data questionnaire, the Mental Health Inventory (MHI-38), the Academic Life Satisfaction Scale (ALLS), the Psychological Vulnerability Scale (PVS), and a question to assess students’ perception of their vulnerability. We found significant gender-related differences (p < .05) in all subscales of MHI-38, the ALLS-Personal Satisfaction subscale, and the self-perception of vulnerability. Overall, freshmen women presented worse scores in all subscales of MHI-38, in ALLS-Personal Satisfaction subscale, and a higher self-perception of vulnerability. These findings emphasize the need to design and implement mental health promotion activities, mainly focused on the needs of freshmen women, in colleges.
- Impact of COVID-19 outbreak on nurses’ mental health: a prospective cohort studyPublication . Sampaio, Francisco; Sequeira, Carlos; Teixeira, L.Objectives: To evaluate variations in nurses’ sleep quality and symptoms of depression, anxiety and stress during the COVID-19 outbreak, and to evaluate whether the presence of potential risk factors influenced these symptoms over time. Methods: This prospective cohort study surveyed nurses three times – surveying personal factors, working conditions, family dynamics, and attitude towards COVID-19 – between March 31 and May 4, 2020. Nurses’ mental health was assessed through Depression Anxiety Stress Scales – short version (DASS-21); their sleep quality was assessed through a 5-point Likert scale question. Results: Nurses' sleep quality and symptoms of depression, anxiety and stress presented a positive variation over the COVID-19 outbreak. The only factors which are directly related to the COVID-19 outbreak and that were associated with the positive variation in nurses’ symptoms of depression, anxiety and stress were the fear to infect others and the fear to be infected (higher fear of being infected or to infect someone corresponded to increased symptoms of depression, anxiety and stress). Conclusions: Although the COVID-19 outbreak seems to have had an immediate impact on nurses' mental health, a psychological adaptation phenomenon was also observed. Future research should focus on assessing nurses’ symptoms of depression, anxiety and stress, after the COVID-19 pandemic, in order to compare and contrast the findings with the results of our study.
- Influência dos estilos de liderança no burnout dos enfermeiros: uma scoping reviewPublication . Loureiro, Rita; Lima, Andreia Maria Novo; Ferreira, Maria Margarida; Moreira, Teresa; Guerra, Maria Manuela; Santos, José Manuel dosObjetivo: identificar quais os estilos de liderança utilizados por enfermeiros gestores e compreender a sua influência no burnout dos enfermeiros no contexto de trabalho. Método: scoping review, realizada em abril de 2021, conduzida de acordo com a metodologia de Joanna Briggs Institute. Dois revisores independentes avaliaram a relevância dos artigos, a extração e síntese dos dados. Resultados: foram identificados 3.532 estudos na pesquisa bibliográfica, dos quais sete estudos apresentaram as características de elegibilidade para a inclusão na revisão. Os estilos de liderança identificados na literatura foram a liderança transformacional e liderança autêntica que revelam um impacto positivo na redução do burnout; a liderança laissez-faire que, pelo contrário, promove um ambiente facilitador do desenvolvimento da síndrome em estudo; a liderança transacional, por sua vez, não demonstrou resultados significativos na diminuição e prevenção de burnout, assim como, a liderança autocrática, carismática e situacional cujos resultados não se demonstraram quantificáveis para a sua prevenção. Conclusão: o estilo de liderança transformacional foi aquele que maior relevância demonstrou tanto na prevenção como diminuição do desenvolvimento de burnout nos enfermeiros.
- Mental health literacy: it is now time to put knowledge into practicePublication . Sampaio, Francisco; Gonçalves, Patrícia; Sequeira, Carlos
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