Percorrer por autor "Talmont, Sophie Anne-Marie Christiane"
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- Alcoholic beverages consumption and periodontium: pathophysiology and clinical implications for periodontal diseases – integrative reviewPublication . Talmont, Sophie Anne-Marie Christiane; Guerra, RitaBackground: The potential impact of alcohol consumption on periodontal health remains insufficiently explored despite growing interest in behavioral risk factors. While the role of tobacco is well established, alcohol's effects on the periodontium are less clearly defined and may involve complex interactions at the microbial, immunological and clinical levels. Objective: This integrative review aimed to assess whether alcohol consumption affects periodontal health by synthesizing data from human studies, animal models and microbiota-focused research. It sought to identify consistent patterns across different methodologies and to evaluate the clinical relevance of alcohol as a risk factor in periodontology. Methods: A comprehensive literature search was conducted in PubMed, Scopus and the Cochrane Library, between April and May 2025, following PRISMA 2020 guidelines. Studies published between 2015 and 2025 in English were included if they investigated the relationship between alcohol and periodontal outcomes. Nine articles were selected for final analysis, covering epidemiological data, microbiota composition, immune responses and periodontal parameters. Results: The included studies showed that alcohol consumption is associated with microbial dysbiosis, increased inflammatory markers and worsening of clinical periodontal indicators. Both human and animal data demonstrated dose-dependent effects, with heavier alcohol intake linked to more pronounced periodontal deterioration. Functional microbial changes and systemic mediators such as liver enzymes and glucose levels were also implicated. These effects were observed even in non-smokers, suggesting an independent role of alcohol. Conclusion: Alcohol consumption may contribute to periodontal disease through both local and systemic mechanisms, including microbial imbalance, immune activation and metabolic changes. Given the consistency of findings across studies, alcohol should be considered in periodontal risk assessment. Further research is needed to clarify causal relationships, to differentiate the effects of beverage types and to evaluate implications for peri-implant health.