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Publication
Microbioma oral humano
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| PPG_24455 | 4.56 MB | Adobe PDF |
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Advisor(s)
Abstract(s)
O microbioma oral humano é constituído por um vasto conjunto de microrganismos
presentes na cavidade oral.
Analisando a cavidade oral podemos verificar que nela existem mais de 700 espécies de
bactérias responsáveis pelo domínio de parte do microbioma humano, tornando-a um
importante local de estudo. É um dos habitats com maior diversidade no corpo humano
onde esses microrganismos se apresentam de forma organizada e estruturada. Estes
habitats estão intimamente relacionados com o desenvolvimento do sistema imunitário e
com a proteção contra agentes patogénicos.
O microbioma oral é único e específico em cada indivíduo, sofrendo variações em
indivíduos diferentes. Na origem da diversidade do microbioma oral estão associados
fatores como genética, dieta e localização geográfica, tendo também grande importância
a localização anatómica e a idade do indivíduo.
O Projeto Microbioma Humano surgiu com a finalidade de identificar diversos
microrganismos presentes no ser humano, bem como compreender os principais fatores
responsáveis pelas suas alterações. O estudo do microbioma oral tem sido possível
graças a novas técnicas moleculares, que ajudaram a ultrapassar certas limitações de
cultivo de determinas espécies bacterianas.
O estudo do microbioma, das interações entre as comunidades microbianas e a sua
relação com o hospedeiro são a chave para a prevenção de certas doenças orais
infeciosas como a cárie dentária e a doença periodontal.
The human oral microbiome consists of a vast array of microorganisms present in the oral cavity. Analyzing the oral cavity it can be seen that there are over 700 species of bacteria responsible for part of the human microbiota domain, making it an important study site. It is one of the most diverse habitats in the human body where these microorganisms are presented in an organized and structured manner. These habitats are closely related to the development of the immune system as well as protection against pathogens. The oral microbiome is unique and specific for each individual, different individuals suffering variations. The origin of the diversity of the oral microbiome are associated factors such as genetics, diet and geographical location, and also have a great importance to anatomical location and the age of the individual. The Human Microbiome Project came up with the purpose of identifying various microorganisms present in humans as well as understing the main factors responsible for their changes. The study of the oral microbiome has been possible thanks to new molecular techniques, which help to overcome certain limitations to the cultivation of determined bacterial species. The study of microbioma, the interactions between microbial communities and its relationship with host are the key to the prevention of certain infectious oral diseases as dental caries and periodontal disease.
The human oral microbiome consists of a vast array of microorganisms present in the oral cavity. Analyzing the oral cavity it can be seen that there are over 700 species of bacteria responsible for part of the human microbiota domain, making it an important study site. It is one of the most diverse habitats in the human body where these microorganisms are presented in an organized and structured manner. These habitats are closely related to the development of the immune system as well as protection against pathogens. The oral microbiome is unique and specific for each individual, different individuals suffering variations. The origin of the diversity of the oral microbiome are associated factors such as genetics, diet and geographical location, and also have a great importance to anatomical location and the age of the individual. The Human Microbiome Project came up with the purpose of identifying various microorganisms present in humans as well as understing the main factors responsible for their changes. The study of the oral microbiome has been possible thanks to new molecular techniques, which help to overcome certain limitations to the cultivation of determined bacterial species. The study of microbioma, the interactions between microbial communities and its relationship with host are the key to the prevention of certain infectious oral diseases as dental caries and periodontal disease.
Description
Keywords
Periodontite Cárie dentária Microbioma oral Patogénese Periodontitis Caries Oral microbiome Pathogenesis