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Publication
Fitoterapia e depressão
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| PPG_12147 | 424.28 KB | Adobe PDF |
Advisor(s)
Abstract(s)
A prevalência de transtornos psiquiátricos, como a depressão é muito comum atualmente e afeta muitas pessoas em todo o mundo. Dado que existem vários eventos adversos associados à utilização de fármacos de síntese, o número de utentes que recorrem à fitoterapia tem aumentado nos últimos anos. Inúmeras fontes de literatura mostram uma variedade de mecanismos de atuação de plantas como Crocus sativus L., Eleutherococcus senticosus, Hypericum perforatum L., Griffonia simplicifolia e Rhodiola rosea que são utilizadas no tratamento de depressão, envolvendo recaptação de monoaminas, que afetam o neurorecetor ou que atuam como moduladores do eixo hipotálamo- hipófise- córtex- suprarrenal.
Por ser um mercado em expansão, tem recebido muita atenção, mas cabe ao farmacêutico fornecer informação ao utente, sustentada em conhecimento científico que ainda é muito limitado pois muitos dos ensaios clínicos realizados têm valor limitado. Os ensaios clínicos efetuados e descritos ou envolvem um pequeno numero de pessoas, ou utilizam modelos não humanos, e acima de tudo utilizam produtos de composição e formulação pouco concreta, o que levanta questões de segurança na utilização de fitofármacos.
The prevalence of psychiatric disorders such as depression is very common these days and affects many people worldwide. Since there are various adverse events associated with the use of synthetic drugs, the number of users who turn to herbal medicine has increased in recent years. Literature sources show a variety of plants such as Crocus sativus L., Eleutherococcus senticosus, Hypericum perforatum L., Griffonia simplicifolia and Rhodiola rosea, describing the actuation mechanisms used in the treatment of depression, involving monoamine reuptake, affecting neuroreceptor or which act as modulators of the hypothalamic pituitary axis adrenal córtex. Being a growing market, it has received much attention, but the pharmacist has the compeled to provide information to the user, supported in scientific knowledge which is very limited, because many of the conducted clinical trials have limited value. The clinical trials either involve a small number of people, or use non-human models, and above all use products of uncertain composition, which raises safety issues in the use of this products.
The prevalence of psychiatric disorders such as depression is very common these days and affects many people worldwide. Since there are various adverse events associated with the use of synthetic drugs, the number of users who turn to herbal medicine has increased in recent years. Literature sources show a variety of plants such as Crocus sativus L., Eleutherococcus senticosus, Hypericum perforatum L., Griffonia simplicifolia and Rhodiola rosea, describing the actuation mechanisms used in the treatment of depression, involving monoamine reuptake, affecting neuroreceptor or which act as modulators of the hypothalamic pituitary axis adrenal córtex. Being a growing market, it has received much attention, but the pharmacist has the compeled to provide information to the user, supported in scientific knowledge which is very limited, because many of the conducted clinical trials have limited value. The clinical trials either involve a small number of people, or use non-human models, and above all use products of uncertain composition, which raises safety issues in the use of this products.
Description
Keywords
Fitoterapia Depressão Phytotherapy Depression