Publication
Long-term negative Psychological Impact of Presymptomatic Testing for Huntington’s Disease
| dc.contributor.author | Leite, Ângela Maria Teixeira | |
| dc.contributor.author | Dinis, Maria Alzira Pimenta | |
| dc.contributor.author | Pinto, Susana Maria Lêdo da Silva | |
| dc.contributor.author | Pinto, Ana Manuela Baldaia Carvalho | |
| dc.contributor.author | Gomes, Ana Isabel Pinheiro | |
| dc.contributor.author | e Sousa, Hélder Fernando Pedrosa | |
| dc.date.accessioned | 2019-09-13T14:52:58Z | |
| dc.date.available | 2019-09-13T14:52:58Z | |
| dc.date.issued | 2017 | |
| dc.description | http://sherpa.ac.uk/romeo/issn/2422-8419/ | pt_PT |
| dc.description.abstract | Presymptomatic Testing (PST) for Huntington’s disease (HD) is available since 1986 and its impact on carriers and non-carriers is not yet fully clear. It is important to understand its psychological impact so that the PST protocols are best suited to the subjects at-risk. Preventing a negative psychological impact is the ultimate purpose of the genetic counselling process. This study addresses the long-term negative psychological impact assessment of PST for HD. The sample consisted of 29 subjects that were 50% at-risk for HD, and had performed the PST for at least three years ago. Participants answered the sociodemographic questionnaire and the Brief Symptom Inventory, the Zung Self-Rating Anxiety Scale, and the Beck Depression Inventory. Although most of the sample does not present clinically significant psychopathology values, 6 subjects present a Positive Symptoms Distress Index value which is equal to or greater than 1.7; 7 subjects present a value which is equal to or greater than 40 of anxiety; and 7 subjects present mild depression. Symptomatic carriers, who underwent the PST less time ago, present worse psychopathological symptoms, depression and anxiety. Subjects with this profile should have a more intense and personalized psychological and social support, aiming to prevent the risk of suicide and to improve the quality of their lives. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | APA: Leite, Â. M. T., Dinis, M. A. P., Pinto, S. M. L. d. S., Pinto, A. M. B. C., Gomes, A. I. P., & e Sousa, H. F. P. (2017). Long-term negative Psychological Impact of Presymptomatic Testing for Huntington’s Disease. Journal of Health, Medicine and Nursing, 34, 1-9. | pt_PT |
| dc.identifier.issn | 2422-8419 | |
| dc.identifier.uri | http://hdl.handle.net/10284/7869 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | International Peer Reviewed Journal and Book Publishing | pt_PT |
| dc.relation.publisherversion | https://iiste.org/Journals/index.php/JHMN/article/view/35145 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Presymptomatic Testing (PST) | pt_PT |
| dc.subject | Preditive genetic testing | pt_PT |
| dc.subject | Huntington´s Disease (HD) | pt_PT |
| dc.subject | Long-term Psychological Impact | pt_PT |
| dc.subject | Late-onset disease | pt_PT |
| dc.title | Long-term negative Psychological Impact of Presymptomatic Testing for Huntington’s Disease | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 9 | pt_PT |
| oaire.citation.startPage | 1 | pt_PT |
| oaire.citation.title | Journal of Health, Medicine and Nursing | pt_PT |
| oaire.citation.volume | 34 | pt_PT |
| person.familyName | Dinis | |
| person.givenName | Maria Alzira Pimenta | |
| person.identifier | 493603 | |
| person.identifier.ciencia-id | 4710-147D-FDAF | |
| person.identifier.orcid | 0000-0002-2198-6740 | |
| person.identifier.rid | F-3309-2011 | |
| person.identifier.scopus-author-id | 55539804000 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isAuthorOfPublication | 1e85592a-e8e2-4aea-bd8e-1007c94388c0 | |
| relation.isAuthorOfPublication.latestForDiscovery | 1e85592a-e8e2-4aea-bd8e-1007c94388c0 |