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Abstract(s)
CADASIL, cuja denominação é Arteriopatia Cerebral Autossómica Dominante com Enfartes Subcorticais e Leucoencefalopatia, é uma patologia genética que afeta os pequenos vasos sanguíneos do cérebro, resultando em múltiplas lesões isquêmicas. Existem 5 principais sintomas para caracterizar a doença: défices cognitivos, enxaqueca com aura, perturbações de humor, eventos isquêmicos subcorticais e apatia. Assim, os objetivos deste estudo são: caracterizar a sintomatologia ansiosa e a sintomatologia depressiva de uma amostra de indivíduos com CADASIL; explorar a relação destas com as variáveis sociodemográficas sexo e idade (Artigo 1) e com a espiritualidade (Artigo 2). Para o efeito, após a obtenção das devidas autorizações, 40 adultos com CADASIL responderam a um Questionário Sociodemográfico, à HADS - Escala Hospitalar de Ansiedade e Depressão (Artigo 1) e à Escala de Avaliação da Espiritualidade em Contextos de Saúde (Artigo 2). Verificou-se maior sintomatologia ansiosa do que depressiva nos participantes e que a mesma era mais frequente no sexo feminino do que no sexo masculino e ia piorando à medida que a idade avançava (Artigo 1). Constatou-se ainda que os pacientes que reportaram níveis mais elevados de espiritualidade na subescala “Esperança e Otimismo” não reportaram sintomatologia depressiva nem sintomatologia ansiosa, ao contrário dos doentes com baixo nível de espiritualidade de acordo com a subescala “Esperança e Otimismo”. Os resultados alcançados reafirmam a necessidade de considerar a espiritualidade, a sintomatologia ansiosa e a sintomatologia depressiva em doentes com CADASIL, sendo importante realizar-se mais estudos neste campo, para fortalecer essas conclusões.
CADASIL, which means Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy, is a genetic pathology that affects the small blood vessels of the brain, resulting in multiple ischaemic lesions. There are 5 main symptoms to characterise the disease: cognitive deficits, migraine with aura, mood disorders, subcortical events and apathy. Thus, the objectives of this study are to characterise the anxiety symptomatology and depressive symptomatology of a sample of individuals with CADASIL; to explore the relationship between these with the sociodemographic variables gender and age (Article 1) and with spirituality (Article 2). For this purpose, after obtaining the necessary authorisations, 40 adults with CADASIL answered a Sociodemographic Questionnaire, the HADS - Hospital Anxiety and Depression Scale (Article 1) and the Scale for the Evaluation of Spirituality in Health Contexts (Article 2). Participants were found to have more anxious than depressive symptoms, which were more common in females than in males and worsened with age (Article 1). It was also found that patients who reported higher levels of spirituality in the "Hope and Optimism" subscale did not report depressive or anxious symptomatology, unlike patients with low levels of spirituality according to the "Hope and Optimism" subscale. The results reaffirm the need to consider spirituality, anxiety symptoms and depressive symptoms in CADASIL patients, being important to carry out further studies in this field to reinforce these conclusions.
CADASIL, which means Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy, is a genetic pathology that affects the small blood vessels of the brain, resulting in multiple ischaemic lesions. There are 5 main symptoms to characterise the disease: cognitive deficits, migraine with aura, mood disorders, subcortical events and apathy. Thus, the objectives of this study are to characterise the anxiety symptomatology and depressive symptomatology of a sample of individuals with CADASIL; to explore the relationship between these with the sociodemographic variables gender and age (Article 1) and with spirituality (Article 2). For this purpose, after obtaining the necessary authorisations, 40 adults with CADASIL answered a Sociodemographic Questionnaire, the HADS - Hospital Anxiety and Depression Scale (Article 1) and the Scale for the Evaluation of Spirituality in Health Contexts (Article 2). Participants were found to have more anxious than depressive symptoms, which were more common in females than in males and worsened with age (Article 1). It was also found that patients who reported higher levels of spirituality in the "Hope and Optimism" subscale did not report depressive or anxious symptomatology, unlike patients with low levels of spirituality according to the "Hope and Optimism" subscale. The results reaffirm the need to consider spirituality, anxiety symptoms and depressive symptoms in CADASIL patients, being important to carry out further studies in this field to reinforce these conclusions.
Description
Keywords
CADASIL Ansiedade Depressão Espiritualidade Anxiety Depression Spirituality