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Mecanismos bioquímicos da formação da cárie: revisão narrativa
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 38391 | 1.62 MB | Adobe PDF |
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Abstract(s)
O objetivo desta tese é realizar um revisão bibliográfica narrativa sobre a cárie dentaria do ponto de vista bioquímica. Em particular, descrever os mecanismos que ocorrem durante a formação da cárie.
A cárie dentária é essencialmente um processo dinâmico que envolve um depósito microbiano, o biofilme dentário na superfície do dente, que sofre várias reacções metabólicas, resultando na dissolução química da substância dentária.
O biofilme dentário é uma comunidade de microrganismos metabolicamente activos que aderiram à superfície do dente. As bactérias do metabolismo do biofilme actuam sobre os hidratos de carbono da dieta, e são produzidos ácidos orgânicos, que dissolvem o componente da superfície dos dentes. O ambiente ácido selecciona os microrganismos mais capazes de resistir a este pH baixo, permitindo a estes organismos prosperar e continuar o processo da cárie, isto é importante por causa do papel do S. mutans no metabolismo dos açúcares, e dos polissacáridos na etiologia e como a dieta e o microbioma oral actuam sobre a incidência da cárie.
The aim of this thesis is to conduct a narrative literature review on dental caries from a biochemical point of view. In particular, to describe the mechanisms that occur during caries formation. Dental caries is essentially a dynamic process involving a microbial deposit, the dental biofilm on the tooth surface, which undergoes various metabolic reactions, resulting in the chemical dissolution of the tooth substance. Dental biofilm is a community of metabolically active microorganisms that have adhered to the tooth surface. The bacteria in the biofilm metabolism act on carbohydrates in the diet, and organic acids are produced, which dissolve the component of the tooth surface. The acidic environment selects those micro-organisms best able to withstand the low pH, allowing these organisms to thrive and continue the caries process. This is important because of the role of S. mutans in sugar metabolism, and polysaccharides in the etiology and how diet and the oral microbiome act on the incidence of caries.
The aim of this thesis is to conduct a narrative literature review on dental caries from a biochemical point of view. In particular, to describe the mechanisms that occur during caries formation. Dental caries is essentially a dynamic process involving a microbial deposit, the dental biofilm on the tooth surface, which undergoes various metabolic reactions, resulting in the chemical dissolution of the tooth substance. Dental biofilm is a community of metabolically active microorganisms that have adhered to the tooth surface. The bacteria in the biofilm metabolism act on carbohydrates in the diet, and organic acids are produced, which dissolve the component of the tooth surface. The acidic environment selects those micro-organisms best able to withstand the low pH, allowing these organisms to thrive and continue the caries process. This is important because of the role of S. mutans in sugar metabolism, and polysaccharides in the etiology and how diet and the oral microbiome act on the incidence of caries.
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Keywords
Streptococcus mutans Biofilme Carbohidratos Cárie