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Publication
Cancro oral e terapias alvo
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| PPG_23684 | 381.66 KB | Adobe PDF |
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Abstract(s)
O cancro oral é definido pela Classificação Internacional de Doenças pelo conjunto de tumores
malignos que afetam qualquer localização da cavidade oral, dos lábios à garganta, incluindo as
amígdalas e a faringe.
É importante referir que o cancro oral é um dos tipos de doença oncológica mais comum a nível
mundial e apresenta uma elevada taxa de mortalidade. De uma forma genérica, esta doença tem
como principais abordagens terapêuticas a intervenção cirúrgica, a radioterapia e a quimioterapia,
ou até mesmo a combinação destas terapias.
Esta dissertação tem como base expor e compreender de forma mais aprofundada as novas terapias
alvo para cancro oral, que atualmente são estudadas e aplicadas como tratamento desta patologia
oncológica e transmitir a importância das mesmas. Pretende-se realçar que estas terapias são
distintas das convencionais, analisando o mecanismo de ação, o tipo de doentes e em que fase são
utilizadas, os seus benefícios, malefícios e resposta por parte da doença.
As terapias inovadoras que estão a ser desenvolvidas apresentam uma influência positiva em
relação à sobrevivência global, à sobrevivência livre de progressão da doença e à qualidade de vida
dos pacientes. Este trabalho trata-se de uma revisão bibliográfica, com recurso à biblioteca da
Faculdade de Ciências da Saúde da Universidade Fernando Pessoa e às bases de dados Pubmed,
Scielo e B-on.
Oral cancer is defined by the International Classification of Diseases by the set of malignant tumors that affect any localization of the oral cavity, from the lips to the throat, including the tonsils and the pharynx. It is important to note that oral cancer is one of the most common types of cancer worldwide and has a high mortality rate. Generally, this disease has as main therapeutic approaches surgical intervention, radiotherapy and chemotherapy, or even the combination of these therapies. This dissertation is based on exposing and comprehending in more depth the new target therapies for oral cancer, which are currently studied and applied as treatment of this oncological pathology and transmit the importance of them. It is intended to emphasize that these therapies are distinct from the conventional ones, analyzing the mechanism of action, the type of patients and in what phase they are used, their benefits, harms and response by the disease. Innovative therapies being developed have a positive influence on overall survival, progression-free survival, and patients' quality of life. This work is a bibliographical review, using the library of the Faculty of Health Sciences of the Fernando Pessoa University and the databases Pubmed, Scielo and B-on.
Oral cancer is defined by the International Classification of Diseases by the set of malignant tumors that affect any localization of the oral cavity, from the lips to the throat, including the tonsils and the pharynx. It is important to note that oral cancer is one of the most common types of cancer worldwide and has a high mortality rate. Generally, this disease has as main therapeutic approaches surgical intervention, radiotherapy and chemotherapy, or even the combination of these therapies. This dissertation is based on exposing and comprehending in more depth the new target therapies for oral cancer, which are currently studied and applied as treatment of this oncological pathology and transmit the importance of them. It is intended to emphasize that these therapies are distinct from the conventional ones, analyzing the mechanism of action, the type of patients and in what phase they are used, their benefits, harms and response by the disease. Innovative therapies being developed have a positive influence on overall survival, progression-free survival, and patients' quality of life. This work is a bibliographical review, using the library of the Faculty of Health Sciences of the Fernando Pessoa University and the databases Pubmed, Scielo and B-on.
Description
Keywords
Cancro oral e terapias alvo Cancro cabeça e pescoço Egfr Anticorpos monoclonais Inibidores tirosina cinase Vegf Via pi3k Targeted therapy and oral cancer Head and neck cancer Egfr Monoclonal antibodies Tyrosine kinase inhibitors Vegf Pi3k pathway