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Intoxicações agudas por medicamentos de uso comum em pediatria
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Abstract(s)
As intoxicações por medicamentos, de forma intencional ou não intencional, são um fator de mortalidade e morbilidade entre as crianças, sendo necessário, muitas das vezes, a hospitalização.
A identificação do agente tóxico, através do conjunto de sinais e sintomas, bem como o historial de exposição, é fundamental para que seja iniciado o tratamento/descontaminação o mais rápido possível de modo a diminuir o tempo de internamento e complicações de saúde.
O tratamento da intoxicação é diferente mediante o composto em causa e passa pelo tratamento sintomático, medidas de descontaminação e aumento da eliminação do tóxico.
Esta dissertação tem como objetivo efetuar uma revisão narrativa dos fármacos, ou grupos farmacoterapêuticos mais relatados em casos de intoxicações na idade pediátrica, destacando-se, em cada caso, as novas abordagens terapêuticas, algumas das quais ainda se encontram em fase de desenvolvimento clínico.
Drug poisoning, whether internationally or not internationally, is an important factor of mortality and morbidity among children, often requiring hospitalization. The identification of the toxic agent, through the set of signs and symptoms, as well as the exposure history, is essential to start the treatment/decontamination, as soon as possible, in order to reduce hospitalization time and health complications. The treatment of intoxication is different according the compound and involves symptomatic treatment, decontamination measures and increased elimination of the toxicant. This dissertation aims to carry out a narrative review of the drugs, or pharmacotherapeutic groups most reported poisoning cases in pediatric age, highlighting, in each case, the new therapeutic approaches, some of which still in the clinical phases.
Drug poisoning, whether internationally or not internationally, is an important factor of mortality and morbidity among children, often requiring hospitalization. The identification of the toxic agent, through the set of signs and symptoms, as well as the exposure history, is essential to start the treatment/decontamination, as soon as possible, in order to reduce hospitalization time and health complications. The treatment of intoxication is different according the compound and involves symptomatic treatment, decontamination measures and increased elimination of the toxicant. This dissertation aims to carry out a narrative review of the drugs, or pharmacotherapeutic groups most reported poisoning cases in pediatric age, highlighting, in each case, the new therapeutic approaches, some of which still in the clinical phases.
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Keywords
Intoxicação aguda Pediatria Tratamento Diagnóstico Analgésicos e antipiréticos Anti-histamínicos e descongestionantes Broncodilatadores Anticonvulsivantes Acute intoxication Pediatric drugs Treatment Diagnosis Analgesics and antipyretics Antihistamines and decongestants Bronchodilators Anticonvulsants