Loading...
Publication
Os desafios do uso medicinal de canábis na Europa
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| Projeto de pós-graduação_42300 | 1.67 MB | Adobe PDF |
Authors
Advisor(s)
Abstract(s)
A Cannabis sativa L. e seus derivados têm uma vasta história de utilização, tanto a nível medicinal como recreativo. É considerada uma das drogas ilícitas mais consumidas a nível mundial e, consequentemente, a comunidade científica tem demonstrado um grande interesse nas potenciais propriedades terapêuticas e aplicações clínicas, que têm vindo a aumentar nas últimas décadas, fomentando alterações na legislação em diversos países da Europa.
A planta canábis possui um elevado número de compostos com propriedades biológicas e farmacológicas importantes, os canabinoides, capazes de se ligar e ativar recetores no corpo humano e desencadear respostas fisiológicas. Estudos científicos têm demonstrado evidências do potencial terapêutico dos canabinoides presentes na planta e os seus benefícios para o tratamento de diversas patologias.
A evolução da legislação da canábis na Europa tem permitido o estabelecimento de regulamentações para minimizar os riscos associados ao emprego inadequado desta planta e possibilitar o seu uso terapêutico. Com as recentes mudanças legislativas a nível global, em alguns países os produtos derivados da canábis já se encontram comercialmente disponíveis, oferecendo uma abordagem farmacológica alternativa. O uso medicinal da canábis na Europa enfrenta desafios legais, regulamentares, científicos e sociais e necessita de uma abordagem holística para garantir que os pacientes tenham acesso seguro e eficaz a esta planta e aos seus derivados.
Com a elaboração desta dissertação, pretende-se realizar uma pesquisa bibliográfica atual sobre as aplicações medicinais da canábis e os desafios que enfrenta em termos de legislação responsável. Para a elaboração do trabalho, procedeu-se a uma revisão da literatura referente às principais propriedades da planta canábis e compostos canabinoides predominantes, vias de administração, aplicações terapêuticas, efeitos adversos, enquadramento regulamentar na Europa e em Portugal e perspetivas futuras.
A Cannabis sativa L. and its derivatives have a long history of use, both medicinally and recreationally. It is considered one of the most widely consumed illicit drugs worldwide and, as a result, the scientific community has shown a great interest in its potential therapeutic properties and clinical applications, which have been increasing in recent decades, leading to changes in legislation in several European countries. The cannabis plant contains a high number of compounds with important biological and pharmacological properties called cannabinoids, which have the ability to activate receptors in the human body and trigger physiological responses. Scientific studies have provided evidence of the therapeutic potential of cannabinoids present in the plant and their benefits for the treatment of various pathologies. The evolution of cannabis legalization in Europe has allowed for the establishment of regulations to minimize the risks associated with improper use of this plant and enable its therapeutic use. With recent legislative changes globally, cannabis-derived products are already available in the market in some countries, offering an alternative pharmacological approach. The medicinal use of cannabis in Europe faces legal, regulatory, scientific, and social challenges and requires a holistic approach to ensure that patients have safe and effective access to the use of this plant and its derivatives. The aim of this dissertation is to conduct current research on the medicinal applications of cannabis use and the challenges it faces in terms of responsible legislation. In the development of this work, a literature review was conducted on the main characteristics of the cannabis plant and the predominant cannabinoids, routes of administration, therapeutic applications, adverse effects, regulatory framework in Europe and Portugal, and future perspectives.
A Cannabis sativa L. and its derivatives have a long history of use, both medicinally and recreationally. It is considered one of the most widely consumed illicit drugs worldwide and, as a result, the scientific community has shown a great interest in its potential therapeutic properties and clinical applications, which have been increasing in recent decades, leading to changes in legislation in several European countries. The cannabis plant contains a high number of compounds with important biological and pharmacological properties called cannabinoids, which have the ability to activate receptors in the human body and trigger physiological responses. Scientific studies have provided evidence of the therapeutic potential of cannabinoids present in the plant and their benefits for the treatment of various pathologies. The evolution of cannabis legalization in Europe has allowed for the establishment of regulations to minimize the risks associated with improper use of this plant and enable its therapeutic use. With recent legislative changes globally, cannabis-derived products are already available in the market in some countries, offering an alternative pharmacological approach. The medicinal use of cannabis in Europe faces legal, regulatory, scientific, and social challenges and requires a holistic approach to ensure that patients have safe and effective access to the use of this plant and its derivatives. The aim of this dissertation is to conduct current research on the medicinal applications of cannabis use and the challenges it faces in terms of responsible legislation. In the development of this work, a literature review was conducted on the main characteristics of the cannabis plant and the predominant cannabinoids, routes of administration, therapeutic applications, adverse effects, regulatory framework in Europe and Portugal, and future perspectives.
Description
Keywords
Cannabis sativa Canabinoides Canábis medicinal Uso terapêutico Legislação Cannabinoids Medicinal cannabis Therapeutic use Legislation