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Sensibilidade dos microorganismos colagenolíticos à solução de clorhexidina: revisão integrativa da literatura
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Objetivo: Avaliar a suscetibilidade dos microorganismos colagenolíticos na presença/ou ausência de clorhexidina (CHX). Metodologia: Pesquisa bibliográfica nas bases de dados PubMed, B-on, ScienceDirect e Cochrane Library. Para garantir a qualidade e consistência da seleção dos artigos, foi seguido o protocolo PRISMA, tendo sido estipulados critérios específicos de inclusão e exclusão. A avaliação metodológica foi realizada através da Escala de QUIN. Resultados: De 1227 artigos identificados, 8 foram incluídos. Identificaram-se limitações relacionadas com a heterogeneidade dos estudos em termos de métodos, tempos de exposição e concentrações, o que dificulta a comparação direta e a síntese de resultados. Conclusão: Existe relação entre a degradação de colagénio e os microorganismos presentes na doença periodontal. A CHX é eficaz a inibir e/ou eliminar esses agentes. Futuros estudos in vitro sobre o tema, devem ser padronizados, com variáveis controladas e espécies bacterianas bem documentadas.
Objective: evaluate the susceptibility of collagenolytic microorganisms in the presence/absence of chlorhexidine. Methodology: Bibliographic search in the PubMed, B-on, ScienceDirect and Cochrane Library databases. To guarantee the quality and consistency of the selection of articles, the PRISMA protocol was followed, and specific inclusion and exclusion criteria were stipulated. The methodological evaluation was carried out using the QUIN Scale. Results: Of the 1227 articles identified, 8 were included. Limitations were identified related to the heterogeneity of the studies in terms of methods, exposure times and concentrations, which makes direct comparison and synthesis of the results difficult. Conclusion: There is a relationship between collagen degradation and the microorganisms present in periodontal disease. CHX is effective at inhibiting and/or eliminating these agents. Future in vitro studies on the subject should be standardized, with controlled variables and well-documented bacterial species.
Objective: evaluate the susceptibility of collagenolytic microorganisms in the presence/absence of chlorhexidine. Methodology: Bibliographic search in the PubMed, B-on, ScienceDirect and Cochrane Library databases. To guarantee the quality and consistency of the selection of articles, the PRISMA protocol was followed, and specific inclusion and exclusion criteria were stipulated. The methodological evaluation was carried out using the QUIN Scale. Results: Of the 1227 articles identified, 8 were included. Limitations were identified related to the heterogeneity of the studies in terms of methods, exposure times and concentrations, which makes direct comparison and synthesis of the results difficult. Conclusion: There is a relationship between collagen degradation and the microorganisms present in periodontal disease. CHX is effective at inhibiting and/or eliminating these agents. Future in vitro studies on the subject should be standardized, with controlled variables and well-documented bacterial species.
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Chlorhexidine Mouthrinse Periodontopathogenic bactéria Prevotella intermedia Porphyromonas gingivalis Treponema In vitro