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Patologia inflamatória da cavidade oral: relevância na oncogénese oral
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Authors
Advisor(s)
Abstract(s)
A oncologia oral é uma preocupação crescente em contexto de saúde pública, com impacto na
Qualidade de Vida do doente oncológico e seus familiares. A sobrevivência tem-se mantido
nos 50% ao longo das 3 últimas décadas.
Pretendeu-se relacionar a presença de patologia inflamatória da cavidade oral como fator de
risco e indicador de mau prognóstico em oncologia oral e propor um plano de investigação na
temática.
Foi realizada uma revisão narrativa sobre o tema (2015-2020), nas bases de dados PubMed,
Bon, Elsevier, Science Direct. Foram usadas 70 referências bibliográficas.
Formularam-se questões de investigação e propõe-se um plano de investigação com vista ao
desenvolvimento de estratégias que possam contribuir para o diagnóstico precoce de cancro
oral na consulta de Medicina Dentária.
Foi construído um questionário para integrar no plano de investigação.
Os fatores de risco em Oncologia Oral estão intimamente relacionados entre si- destaca-se a capacidade de na sua maioria, contribuírem para a inflamação de origem extrínseca no microambiente tumoral. A patologia inflamatória crónica e o microbioma da cavidade oral tem relevância em oncologia oral e podem ser usados como biomarcadores, sinalizando pacientes de maior risco. O Médico Dentista pode fazer toda a diferença no acompanhamento do doente oncológico e na promoção da literacia em saúde e cancro oral, junto dos seus colaboradores, dos seus pares e dos seus doentes- e a literacia é uma arma poderosa na prevenção do cancro oral.
The oral oncology is a growing concern in the context of public health, with an impact in the cancer patient's quality of life and its family. The survival has been fixed at 50% over the past 3 decades. This paper intends to relate the presence of an inflammatory pathology of the oral cavity as a risk factor and an indicator of bad prognosis in oral oncology and suggest a research plan in this area. A proofreading was performed about the theme (2015-2020), in the databases PubMed, Bon, Elsevier, and Science Direct. 70 bibliographic references were used. Investigation questions were formulated and a research plan is proposed so as to develop strategies that might contribute to the untimely diagnosis of the oral cancer in Dentistry's appointment. A survey was put together to include in the research plan. The Oral oncology's risk factors are closely interrelated - the ability of the majority to mostly contribute to inflammation of extrinsic origin in the tumor microenvironment is emphasised. Chronic inflammatory pathology and the oral cavity microbiome are relevant in oral oncology and can be used as biomarkers, flagging patients at higher risk. The Dentist can matter in following cancer patients and promoting health and oral cancer literacy with their employees, peers and patients - and literacy is a powerful weapon in preventing oral cancer.
The oral oncology is a growing concern in the context of public health, with an impact in the cancer patient's quality of life and its family. The survival has been fixed at 50% over the past 3 decades. This paper intends to relate the presence of an inflammatory pathology of the oral cavity as a risk factor and an indicator of bad prognosis in oral oncology and suggest a research plan in this area. A proofreading was performed about the theme (2015-2020), in the databases PubMed, Bon, Elsevier, and Science Direct. 70 bibliographic references were used. Investigation questions were formulated and a research plan is proposed so as to develop strategies that might contribute to the untimely diagnosis of the oral cancer in Dentistry's appointment. A survey was put together to include in the research plan. The Oral oncology's risk factors are closely interrelated - the ability of the majority to mostly contribute to inflammation of extrinsic origin in the tumor microenvironment is emphasised. Chronic inflammatory pathology and the oral cavity microbiome are relevant in oral oncology and can be used as biomarkers, flagging patients at higher risk. The Dentist can matter in following cancer patients and promoting health and oral cancer literacy with their employees, peers and patients - and literacy is a powerful weapon in preventing oral cancer.
Description
Keywords
Oncologia oral Inflamação Fatores de risco Epidemiologia Microambiente tumoral Oral oncology Inflammation Risk factors Epidemiology Tumor microenvironment