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Publication
Regeneração periodontal de defeitos intra-ósseos com células estaminais de origem dentária
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| PPG_31098 | 311.35 KB | Adobe PDF |
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Abstract(s)
Objetivo: Avaliar a eficácia da utilização de células estaminais de origem dentária na regeneração de defeitos periodontais intra-ósseos.
Materiais e métodos: A pesquisa, na base de dados da PubMed, restringiu-se a artigos em português e inglês, sem limites temporais. Incluíram-se revisões sistemáticas, meta-análises e ensaios clínicos em animais e humanos. A estratégia de pesquisa resultou em 8 artigos.
Resultados: A escassa literatura disponível defende que a utilização de células estaminais de origem dentária parece promissora e segura. Os resultados são, numa perspetiva geral, positivos, verificando-se ganho de inserção clínico, aumento de volume gengival, mineralização óssea e melhoria dos sinais clínicos.
Conclusões: São necessários mais estudos para validar os achados e aferir (ou refutar) uma eficácia superior das técnicas que usam células estaminais na regeneração de defeitos intraósseos, em detrimento de outras.
Objective: To evaluate the effeciency of the use of stem cells of dental origin in the regeneration of intraosseous periodontal defects. Materials and methods: The survey, in the PubMed database, was restricted to articles in Portuguese and English, with no time limits. Systematic reviews, meta-analyzes and clinical trials in animals and humans were included. The search strategy resulted in 8 articles. Results: The scarce available literature argues that the use of stem cells of dental origin seems promising and safe. The results are, from a general perspective, positive, with clinical insertion gain, gingival volume increase, bone mineralization and improvement of clinical signs. Conclusions: More studies will be needed to validate the findings and to gauge (or refute) superior efficacy of stem cell techniques in regenerating intraosseous defects, to the detriment of others.
Objective: To evaluate the effeciency of the use of stem cells of dental origin in the regeneration of intraosseous periodontal defects. Materials and methods: The survey, in the PubMed database, was restricted to articles in Portuguese and English, with no time limits. Systematic reviews, meta-analyzes and clinical trials in animals and humans were included. The search strategy resulted in 8 articles. Results: The scarce available literature argues that the use of stem cells of dental origin seems promising and safe. The results are, from a general perspective, positive, with clinical insertion gain, gingival volume increase, bone mineralization and improvement of clinical signs. Conclusions: More studies will be needed to validate the findings and to gauge (or refute) superior efficacy of stem cell techniques in regenerating intraosseous defects, to the detriment of others.
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Keywords
Stem cells Intrabony defects Bone regeneration Periodontal disease