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Bioinformática aplicada à extracção de informação do genoma
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| PPG_19946 | 1.07 MB | Adobe PDF |
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Abstract(s)
Muito provavelmente uma das técnicas mais importantes nos dias de hoje, para um biólogo molecular é a sequenciação. Esta técnica permite identificar a sequência dos genes presentes num genoma de interesse.
Esta metodologia passou por várias evoluções que se traduziram nas técnicas de primeira, segunda e terceira geração, sendo esta última de tal forma inovadora que permite a sequência de um genoma em menor tempo possível.
A tecnologia de sequenciação pode ser aplicada ao genoma, denominando-se esta área de Genómica, aplicada mRNA denominando-se de Transcriptómica e aplicada a nível das proteínas, a Proteómica.
Com o objectivo de armazenar toda esta informação, proveniente dos dados extraídos pelos métodos de análise genética, desenvolveram-se Bases de Dados capazes de englobar todo este fluxo de dados para posterior consulta e análise. Criou-se, assim, a Bioinformática.
A Bioinformática apresenta-se como uma tecnologia que engloba áreas como a Biologia Molecular, a epidemiologia, matemática e Informática. Disponibiliza informação sempre actualizada e em linguagem universal, que pode ser consultada por qualquer investigador em qualquer parte do mundo.
Com isto o presente trabalho tem como objectivo elucidar sobre as diferentes tipos de informação que se pode extrair do material genético, e de que forma podem contribuir para o melhoramento da Saúde Pública.
Most likely one of the most important techniques nowadays , for a molecular biologist, is sequencing . This technique allows the identification of gene sequences present in the genome of interest. This methodology has undergone several developments which resulted in the techniques of first, second and third generation , the third one being so innovative that allows the sequence of a genome in shortest possible time . The sequencing technology may be applied to genome, this area being named Genomics, applied to mRNA called Transcriptomic and in proteins, the Proteomics . In order to store all this information from the data derived by methods of genetic analysis have developed databases able to encompass all this data stream for later retrieval and analysis. Was created the Bioinformatics . Bioinformatics is presented as a technology that encompasses areas such as molecular biology, epidemiology , mathematics and computer science. It offers up to date information and universal language that can be consulted by any researcher anywhere in the world. With this, the present work aims to elucidate the different types of information that can be extracted from the genetic material, and how they can contribute to the improvement of public health.
Most likely one of the most important techniques nowadays , for a molecular biologist, is sequencing . This technique allows the identification of gene sequences present in the genome of interest. This methodology has undergone several developments which resulted in the techniques of first, second and third generation , the third one being so innovative that allows the sequence of a genome in shortest possible time . The sequencing technology may be applied to genome, this area being named Genomics, applied to mRNA called Transcriptomic and in proteins, the Proteomics . In order to store all this information from the data derived by methods of genetic analysis have developed databases able to encompass all this data stream for later retrieval and analysis. Was created the Bioinformatics . Bioinformatics is presented as a technology that encompasses areas such as molecular biology, epidemiology , mathematics and computer science. It offers up to date information and universal language that can be consulted by any researcher anywhere in the world. With this, the present work aims to elucidate the different types of information that can be extracted from the genetic material, and how they can contribute to the improvement of public health.