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Publication
Efeito da frutose na síndrome metabólica
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| TC_25695 | 337.91 KB | Adobe PDF |
Authors
Advisor(s)
Abstract(s)
Introdução: A síndrome metabólica (SM) é considerada uma constelação de fatores de risco cardiometabólicos que incluem dislipidemia, resistência à insulina (RI), hipertensão arterial (HTA), intolerância à glicose, obesidade abdominal e NAFLD (Estateose hepática não alcoólica), associados a um risco aumentado de diabetes mellitus tipo 2 (DM2) e doenças cardiovasculares (DCV). A frutose é considerada uma das causas para o aumento de incidência desta síndrome.
Objetivo: Perceber qual o impacto da ingestão da frutose nos componentes da SM.
Métodos: A revisão da literatura foi realizada através de pesquisas feitas na base de dados Pubmed. A pesquisa decorreu entre março e junho de 2015 e os termos utilizados foram: “fructose, metabolic syndrome”, “metabolic effects of fructose” e “fructose, NAFLD”. Foram incluídos nesta revisão sistemática da literatura 23 artigos.
Resultados: O consumo de frutose teve impacto em quase todos os componentes da SM, estando associado a aumentos dos triglicerídeos plasmáticos e da glicemia, bem como a diminuição da sensibilidade à insulina e das concentrações do colesterol HDL. Por sua vez, não se observaram efeitos significativos relativamente à pressão arterial.
Conclusão: O consumo de frutose parece ter efeitos adversos em quase todos os componentes da SM.
Background: Metabolic syndrome (MS) is considered a constellation of cardiometabolic risk factors including dyslipidemia, insulin resistance (IR), high blood pressure (hypertension), glucose intolerance, abdominal obesity and NAFLD (non-alcoholic fatty liver disease), associated with an increased risk of type 2 diabetes mellitus (DM2) and cardiovascular disease (CVD). Fructose is considered one of the causes for the increased incidence of this syndrome. Objective: To understand the impact of fructose intake in MS components. Methods: A literature review was conducted through surveys in Pubmed database. The survey took place between March and June 2015 and the terms used were "fructose, metabolic syndrome," "metabolic effects of fructose" and "fructose, NAFLD." They were included in this systematic literature review 23 articles. Results: Fructose consumption has impacted almost all components of MS and it is associated with increases in plasma triglycerides and blood glucose, and decreased insulin sensitivity and HDL cholesterol concentrations. In turn, there were no significant effects with respect to blood pressure. Conclusion: The fructose consumption seems to have adverse effects on almost all components of MS.
Background: Metabolic syndrome (MS) is considered a constellation of cardiometabolic risk factors including dyslipidemia, insulin resistance (IR), high blood pressure (hypertension), glucose intolerance, abdominal obesity and NAFLD (non-alcoholic fatty liver disease), associated with an increased risk of type 2 diabetes mellitus (DM2) and cardiovascular disease (CVD). Fructose is considered one of the causes for the increased incidence of this syndrome. Objective: To understand the impact of fructose intake in MS components. Methods: A literature review was conducted through surveys in Pubmed database. The survey took place between March and June 2015 and the terms used were "fructose, metabolic syndrome," "metabolic effects of fructose" and "fructose, NAFLD." They were included in this systematic literature review 23 articles. Results: Fructose consumption has impacted almost all components of MS and it is associated with increases in plasma triglycerides and blood glucose, and decreased insulin sensitivity and HDL cholesterol concentrations. In turn, there were no significant effects with respect to blood pressure. Conclusion: The fructose consumption seems to have adverse effects on almost all components of MS.
Description
Trabalho Complementar apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de licenciada em Ciências da Nutrição
Keywords
Frutose Síndrome metabólica Fructose Metabolic syndrome