Publication
NMR-based metabolomics studies of human prostate cancer tissue
| dc.contributor.author | Lima, Ana Rita | |
| dc.contributor.author | Pinto, Joana | |
| dc.contributor.author | Bastos, Maria de Lourdes | |
| dc.contributor.author | Carvalho, Márcia | |
| dc.contributor.author | Guedes de Pinho, Paula | |
| dc.date.accessioned | 2021-07-02T11:10:32Z | |
| dc.date.available | 2021-07-02T11:10:32Z | |
| dc.date.issued | 2018 | |
| dc.description.abstract | Prostate cancer (PCa) is one of the most prevalent cancers in men worldwide. Serum prostate-specific antigen (PSA) remains the most used biomarker in the detection and management of patients with PCa, in spite of the problems related with its low specificity, false positive rate and overdiagnosis. Furthermore, PSA is unable to discriminate indolent from aggressive PCa, which can lead to overtreatment. Early diagnosed and treated PCa can have a good prognosis and is potentially curable. Therefore, the discovery of new biomarkers able to detect clinically significant aggressive PCa is urgently needed. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.doi | 10.1007/s11306-018-1384-2 | pt_PT |
| dc.identifier.issn | 1573-3882 | |
| dc.identifier.uri | http://hdl.handle.net/10284/10018 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Springer | pt_PT |
| dc.relation | This work received financial support from the European Union (FEDER funds POCI/01/0145/FEDER/007728) and National Funds (FCT/MEC, Fundação para a Ciência e a Tecnologia and Ministério da Educação e Ciência) under the Partnership Agreement PT2020 UID/MULTI/04378/2013. The study is a result of the project NORTE-01-0145-FEDER-000024, supported by Norte Portugal Regional Operational Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement (DESignBIOtecHealth—New Technologies for three Health Challenges of Modern Societies: Diabetes, Drug Abuse and Kidney Diseases), through the European Regional Development Fund (ERDF). A.R.L. thanks to FCT for her PhD Grant (SFRH/BD/123012/2016) and M.C. also acknowledges FCT through the UID/MULTI/04546/2016 project. | pt_PT |
| dc.subject | Prostate cancer | pt_PT |
| dc.subject | Metabolomics | pt_PT |
| dc.subject | Tissues | pt_PT |
| dc.subject | Nuclear magnetic resonance spectroscopy | pt_PT |
| dc.title | NMR-based metabolomics studies of human prostate cancer tissue | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.issue | 7 | pt_PT |
| oaire.citation.startPage | 88 | pt_PT |
| oaire.citation.title | Metabolomics | pt_PT |
| oaire.citation.volume | 14 | pt_PT |
| person.familyName | Carvalho | |
| person.givenName | Marcia | |
| person.identifier | 2017111 | |
| person.identifier.ciencia-id | 8B10-171E-E63E | |
| person.identifier.orcid | 0000-0001-9884-4751 | |
| person.identifier.rid | D-5999-2013 | |
| person.identifier.scopus-author-id | 7201413997 | |
| rcaap.rights | closedAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isAuthorOfPublication | 3837b828-ba57-47f7-a811-cce65e4922c6 | |
| relation.isAuthorOfPublication.latestForDiscovery | 3837b828-ba57-47f7-a811-cce65e4922c6 |
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