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Publication
Proteínas derivadas de matriz de esmalte (Emdogain®) em defeitos infra-ósseos: revisão narrativa
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| PPG_29172 | 815.29 KB | Adobe PDF |
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Abstract(s)
Objetivo: Avaliar a eficácia das proteínas derivadas da matriz de esmalte (Emdogain®) na regeneração periodontal de defeitos infra-ósseos.
Materiais e Métodos: Realizou-se uma pesquisa na base de dados da PubMed. Foram apenas selecionadas revisões sistemáticas e meta-análises, publicadas nos últimos 10 anos, em humanos, em inglês ou português. A pesquisa resultou num total de 7 artigos.
Resultados: O tratamento de defeitos infra-ósseos com proteínas derivadas da matriz de esmalte, isoladamente ou em terapia de combinação, apresenta resultados positivos na redução da profundidade de sondagem, no ganho do nível de inserção clínico e no preenchimento ósseo. Contudo os resultados ainda estão associados a alguma heterogeneidade e risco de viés.
Conclusão: As proteínas derivadas da matriz de esmalte apresentam-se como uma alternativa válida na resolução de defeitos infra-ósseos. No entanto, mais estudos são necessários para tecer conclusões definitivas e permitir a elaboração de guidelines com alto grau de evidência científica.
Aim: To evaluate the efficacy of the use of enamel matrix proteins (Emdogain®) in infra-bony defects, regarding the periodontal regeneration. Materials and Methods: We carried out a bibliographic search using the PubMed database. The selection was based on articles of systematic review and meta-analysis, in the last 10 years based on human beings and published in English or Portuguese. The research resulted in a total of 7 articles. Results: The treatment of infra-bony defects with enamel matrix proteins (Emdogain®), alone or in combination therapy, shows scientific evidence on the reduction of probing depth, gain of clinical insertion level and bone filling. However, some heterogeneity of results is still associated. Conclusion: The enamel matrix proteins are presented as a valid alternative to the treatment of infra-bony defects. However, more studies are needed in order to allow guidelines elaboration, based on high scientific evidence.
Aim: To evaluate the efficacy of the use of enamel matrix proteins (Emdogain®) in infra-bony defects, regarding the periodontal regeneration. Materials and Methods: We carried out a bibliographic search using the PubMed database. The selection was based on articles of systematic review and meta-analysis, in the last 10 years based on human beings and published in English or Portuguese. The research resulted in a total of 7 articles. Results: The treatment of infra-bony defects with enamel matrix proteins (Emdogain®), alone or in combination therapy, shows scientific evidence on the reduction of probing depth, gain of clinical insertion level and bone filling. However, some heterogeneity of results is still associated. Conclusion: The enamel matrix proteins are presented as a valid alternative to the treatment of infra-bony defects. However, more studies are needed in order to allow guidelines elaboration, based on high scientific evidence.
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Keywords
Emdogain EMD Proteínas derivadas da matriz de esmalte Defeitos infra-ósseos Regeneração periodontal EMD Enamel matrix proteins Infrabony defects Periodontal regeneration