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Relação entre a colonização por MRSA e IACS
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Abstract(s)
Staphylococcus aureus resistente à meticilina (MRSA) é considerada uma bactéria multirresistente, responsável por várias infeções representando assim um problema de saúde pública. Embora, inicialmente estas bactérias tenham sido identificadas principalmente em pacientes internados em hospitais, nos últimos anos apareceram novas estirpes de MRSA associadas a infeções graves na comunidade. Estas estirpes estão correlacionadas com potentes fatores de virulência e resistência aos antibióticos. A colonização por MRSA contribui para o desenvolvimento de infeções causadas por esta bactéria, visto a existência do microrganismo de forma permanente ou intermitente na microflora humana agrava o risco de contrair infeção e os sintomas causados por esta. A descolonização e os protocolos de controlo da infeção têm de ser implementados para reduzir o desenvolvimento de resistências e ajudar na erradicação da bactéria nos hospitais e na comunidade. Em síntese, para controlar e tratar as infeções causadas por esta bactéria é essencial o desenvolvimento de novos antibióticos e novas técnicas de combate à infeção.
Os objetivos desta revisão bibliográfica foram caracterizar S. aureus e MRSA, entender a relação entre a colonização por MRSA e IACS, compreender os métodos de deteção laboratorial e os métodos que têm sido utilizados para prevenir e tratar as infeções causadas por este microrganismo.
Methicillin-resistant Staphylococcus aureus (MRSA) are considered multidrug-resistant bacteria, responsible for several infections, thus representing a public health problem. Although initially these bacteria were mainly identified in patients admitted to hospitals, in recent years new strains of MRSA have appeared, associated with serious infections in the community. These strains are correlated with potent virulence factors and antibiotic resistance. Colonization by MRSA contributes to the development of infections caused by this bacterium, as the existence of the microorganism permanently or intermittently in the human microflora aggravates the risk of contracting infection and the symptoms caused by it. Decolonization and infection control protocols need to be implemented to reduce the development of resistance and help eradicate the bacteria in hospitals and the community. In short, to control and treat infections caused by this bacterium, it is essential to develop new antibiotics and new techniques to fight infection. The objectives of this literature review were to characterize S. aureus and MRSA, understand the relationship between colonization by MRSA and HAIs, understand the laboratory detection methods and the methods that have been used to prevent and treat infections caused by this microorganism.
Methicillin-resistant Staphylococcus aureus (MRSA) are considered multidrug-resistant bacteria, responsible for several infections, thus representing a public health problem. Although initially these bacteria were mainly identified in patients admitted to hospitals, in recent years new strains of MRSA have appeared, associated with serious infections in the community. These strains are correlated with potent virulence factors and antibiotic resistance. Colonization by MRSA contributes to the development of infections caused by this bacterium, as the existence of the microorganism permanently or intermittently in the human microflora aggravates the risk of contracting infection and the symptoms caused by it. Decolonization and infection control protocols need to be implemented to reduce the development of resistance and help eradicate the bacteria in hospitals and the community. In short, to control and treat infections caused by this bacterium, it is essential to develop new antibiotics and new techniques to fight infection. The objectives of this literature review were to characterize S. aureus and MRSA, understand the relationship between colonization by MRSA and HAIs, understand the laboratory detection methods and the methods that have been used to prevent and treat infections caused by this microorganism.
Description
Projeto de Graduação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciada em Análises Clínicas e Saúde Pública
Keywords
IACS MRSA Staphylococcus aureus Infeções estafilocócias Staphylococcus aureus Staphylococcal infections