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Publication
PeptĂdeos como alternativas terapĂȘuticas
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| PPG_35047 | 6.02 MB | Adobe PDF |
Authors
Advisor(s)
Abstract(s)
Nos Ășltimos anos tem havido um aumento significativo de aparecimento de estirpes,
mecanismos de resistĂȘncia que tem conferido resistĂȘncia bacteriana a inĂșmeros antibiĂłticos
convencionais, assim as opçÔes terapĂȘuticas tendem a encurtar cada vez mais e a possibilidade
de escolha dos antibióticos adequados torna-se cada vez menor. Os péptidos possuem vårios
mecanismos, atuando na membrana das bactérias, verificando-se uma alternativa a esses
problemas existentes.
Desta forma, o estudo sobre a utilização de PĂ©ptideos Antimicrobianos (AMPs do inglĂȘs
Antimicrobial peptides) tornou-se impreterĂvel devido a todo o potencial que apresentam, pois
para além da sua atividade antimicrobiana também possuem ação anti-inflamatória e
imunolĂłgica.
In recent years there has been a significant increase in the appearance of strains, resistance mechanisms that provide bacterial resistance to the numerous conventional antibiotics, as well as therapeutic options tend to shorten more and more and the possibility of choosing the appropriate antibiotics becomes less and less. The peptides have several mechanisms, acting on the bacterial membrane, proving an alternative to these existing problems. Thus, the study on the use of Antimicrobial Peptides (AMPs from English Antimicrobial peptides) became imperative due to all the potential they present, because in addition to their antimicrobial activity they also have anti-inflammatory and immunological action.
In recent years there has been a significant increase in the appearance of strains, resistance mechanisms that provide bacterial resistance to the numerous conventional antibiotics, as well as therapeutic options tend to shorten more and more and the possibility of choosing the appropriate antibiotics becomes less and less. The peptides have several mechanisms, acting on the bacterial membrane, proving an alternative to these existing problems. Thus, the study on the use of Antimicrobial Peptides (AMPs from English Antimicrobial peptides) became imperative due to all the potential they present, because in addition to their antimicrobial activity they also have anti-inflammatory and immunological action.
Description
Keywords
AMP ResistĂȘncia bacteriana PeptĂdeos antimicrobianos ResistĂȘncia a antibiĂłticos CAMP BactĂ©rias multirresistentes PĂ©ptidos antimicrobianos Mecanismos de ação AMPs AMP Bacterial resistance Antimicrobial peptides Antibiotic resistance CAMP Multidrug-resistant bacteria Antimicrobial peptides Mechanism of action