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O efeito dos agentes branqueadores nas proteínas da dentina: revisão integrativa
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| Projeto de pós-graduação_41227 | 411.41 KB | Adobe PDF |
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Resumo(s)
Numa sociedade onde a aparência desempenha um papel essencial, um sorriso deslumbrante tornou-se um critério estético procurado por muitas pessoas. A crescente procura por dentes mais brancos levou à crescente popularidade dos tratamentos de branqueamento dentário, tanto no consultório como em casa. No entanto, apesar da sua eficácia estética, estes tratamentos não são isentos de consequências. Em particular, os agentes branqueadores, como o peróxido de hidrogénio ou o peróxido de carbamida, podem alterar a estrutura da dentina, modificando as suas proteínas constituintes.
Objetivo: Estudar os efeitos do branqueamento dentário nas propriedades da dentina e nas suas proteínas. O objetivo é compreender o impacto e os efeitos adversos do branqueamento dentário e encontrar alternativas menos invasivas.
Métodos: Foi desenvolvida uma pesquisa integrativa da literatura, com recurso às bases de dados PubMed, Science Direct e Google Scholar. Esta pesquisa seguiu critérios definidos de inclusão e exclusão, considerando apenas estudos que investigaram os efeitos do branqueamento sobre a dentina. As referências foram triadas e selecionadas com base em critérios de elegibilidade, sendo os artigos em texto completo avaliados para possível inclusão e posteriormente resumidos.
Resultados: O colagénio tipo I é a principal proteína da dentina e é essencial para a sua resistência. Durante o branqueamento dentário, agentes como o peróxido de hidrogénio e de carbamida podem degradar esta proteína, comprometendo a estrutura da dentina, causando sensibilidade e efeitos citotóxicos. Também afetam outras proteínas cruciais, como DSPP e DMP1 e ativam enzimas que aceleram a degradação da matriz dentinária.
Conclusões: Este estudo mostra que o branqueamento dentário, embora eficaz esteticamente, pode causar danos significativos à dentina. É fundamental aplicar protocolos adequados e personalizar a avaliação de risco, com foco em tratamentos mais seguros e eficazes a longo prazo.
In a society where appearance plays an essential role, a dazzling smile has become an aesthetic criterion sought by many people. The growing demand for whiter teeth has led to the growing popularity of dental whitening treatments, both in the dental office and at home. However, despite their aesthetic effectiveness, these treatments are not without consequences. In particular, bleaching agents such as hydrogen peroxide or carbamide peroxide can alter the structure of dentin by modifying its constituent proteins. Objective: To study the effects of dental whitening on the properties of dentin and its proteins. The aim is to understand the impact and adverse effects of dental whitening and to find less invasive alternatives. Methods: An integrative literature search was conducted using the PubMed, Science Direct and Google Scholar databases. This search followed defined inclusion and exclusion criteria, considering only studies that investigated the effects of bleaching on dentin. References were screened and selected based on eligibility criteria, and full-text articles were assessed for possible inclusion and subsequently summarized. Results: Type I collagen is the main protein of dentin and is essential for its resistance. During tooth whitening, agents such as hydrogen and carbamide peroxide can degrade this protein, compromising the structure of dentin, causing sensitivity and cytotoxic effects. They also affect other crucial proteins such as DSPP and DMP1 and activate enzymes that accelerate the degradation of the dentin matrix. Conclusions: This study shows that tooth whitening, although effective aesthetically, can cause significant damage to dentin. It is essential to apply appropriate protocols and personalize the risk assessment, focusing on safer and more effective treatments in the long term.
In a society where appearance plays an essential role, a dazzling smile has become an aesthetic criterion sought by many people. The growing demand for whiter teeth has led to the growing popularity of dental whitening treatments, both in the dental office and at home. However, despite their aesthetic effectiveness, these treatments are not without consequences. In particular, bleaching agents such as hydrogen peroxide or carbamide peroxide can alter the structure of dentin by modifying its constituent proteins. Objective: To study the effects of dental whitening on the properties of dentin and its proteins. The aim is to understand the impact and adverse effects of dental whitening and to find less invasive alternatives. Methods: An integrative literature search was conducted using the PubMed, Science Direct and Google Scholar databases. This search followed defined inclusion and exclusion criteria, considering only studies that investigated the effects of bleaching on dentin. References were screened and selected based on eligibility criteria, and full-text articles were assessed for possible inclusion and subsequently summarized. Results: Type I collagen is the main protein of dentin and is essential for its resistance. During tooth whitening, agents such as hydrogen and carbamide peroxide can degrade this protein, compromising the structure of dentin, causing sensitivity and cytotoxic effects. They also affect other crucial proteins such as DSPP and DMP1 and activate enzymes that accelerate the degradation of the dentin matrix. Conclusions: This study shows that tooth whitening, although effective aesthetically, can cause significant damage to dentin. It is essential to apply appropriate protocols and personalize the risk assessment, focusing on safer and more effective treatments in the long term.
Descrição
Palavras-chave
Branqueamento dentário Dentina Peróxido de hidrogénio Risco de branqueamento Teeth whitening Dentin Hydrogen peroxide Bleaching risk