Publication
Inducing apoptosis in cancer therapy
| dc.contributor.author | Moreira, Maria Avides | por |
| dc.date.accessioned | 2008-07-16T14:24:30Z | por |
| dc.date.accessioned | 2011-10-06T14:52:01Z | |
| dc.date.available | 2008-07-16T14:24:30Z | por |
| dc.date.available | 2011-10-06T14:52:01Z | |
| dc.date.issued | 2005 | por |
| dc.description.abstract | Every cell in a multicellular organism has the potential to die by apoptosis. Treatment of cancer cells with tumour necrosis factor - can induce an apoptotic signal leading to the death of these cells; however, many malignancies are resistant to the effects of TNF-α. Overexpression of FLIP, a protein that blocks the caspase activity of FLICE, mediates the observed resistance. Thus, FLIP, which normally prevents inappropriate apoptosis, may become a tumour progression factor. | por |
| dc.format | Article | por |
| dc.identifier.citation | Revista da Faculdade de Ciências da Saúde. Porto. ISSN 1646-0480. 2 (2005) 55-62. | por |
| dc.identifier.issn | 1646-0480 | por |
| dc.identifier.uri | http://hdl.handle.net/10284/547 | por |
| dc.language.iso | eng | por |
| dc.publisher | Edições Universidade Fernando Pessoa | por |
| dc.relation.ispartofseries | Revista da Faculdade de Ciências da Saúde | por |
| dc.relation.ispartofseries | 2 | por |
| dc.title | Inducing apoptosis in cancer therapy | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |