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Fatty Acid Profile of Human Milk of Portuguese Lactating Women: Prospective Study from the 1st to the 16th Week of Lactation

dc.contributor.authorRibeiro, M.
dc.contributor.authorBalcão, Victor
dc.contributor.authorGuimaraes, H.
dc.contributor.authorRocha, G.
dc.contributor.authorMoutinho, Carla
dc.contributor.authorMatos, Carla
dc.contributor.authorAlmeida, Cristina
dc.contributor.authorCasal, S.
dc.contributor.authorGuerra, A.
dc.date.accessioned2019-12-24T11:17:47Z
dc.date.available2019-12-24T11:17:47Z
dc.date.issued2008
dc.description.abstractBackground/Aims: Fatty acid (FA) composition varies over the course of the day and during lactation. The aim of this study was to evaluate FA composition and its compositional stability in human milk, from day 7 to week 16 of lactation. Methods: Human milk was collected from all feedings over 24 h at day 7 and weeks 4, 8, 12 and 16 of lactation in 31 lactating women. FAs were analyzed through gas chromatography. Comparisons were made with analysis of variance. Results: Total monounsaturated FAs decreased from 33.04 ± 2.58% wt/wt at day 7 to 31.48 ± 3.32% wt/wt at week 16 of lactation, much at the expenses of the decrease in the major monounsaturated FA found in human milk, oleic acid. Main polyunsaturated FAs n-6 and n-3 showed fluctuations from day 7 up to week 16 of lactation, but with no statistical significance. Arachidonic acid significantly decreased from transitional to mature milk. Conclusions: The FA profile obtained throughout the study time points presented very low levels of oleic acid and very high linoleic acid/α-linoleic acid ratios which reflect recent changes in Portuguese women’s food patterns. Despite this, the ascorbate/dehydroascorbate ratio remained constant during the study, suggesting a protective metabolic mechanism.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1159/000156597pt_PT
dc.identifier.issn0250-6807
dc.identifier.issn1421-9697
dc.identifier.urihttp://hdl.handle.net/10284/8331
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherKarger Publisherspt_PT
dc.relation.publisherversionhttps://www.karger.com/Article/Abstract/156597pt_PT
dc.subjectAdultpt_PT
dc.subjectAscorbic Acidpt_PT
dc.subjectChromatography, Gaspt_PT
dc.subjectDehydroascorbic Acidpt_PT
dc.subjectFatty Acidspt_PT
dc.subjectFemalept_PT
dc.subjectHumanspt_PT
dc.subjectLactationpt_PT
dc.subjectMilk, Humanpt_PT
dc.subjectPostpartum Periodpt_PT
dc.subjectReference Valuespt_PT
dc.subjectTime Factorspt_PT
dc.subjectYoung Adultpt_PT
dc.subjectFeeding Behaviorpt_PT
dc.titleFatty Acid Profile of Human Milk of Portuguese Lactating Women: Prospective Study from the 1st to the 16th Week of Lactationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage56pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage50pt_PT
oaire.citation.titleAnnals of Nutrition and Metabolismpt_PT
oaire.citation.volume53pt_PT
person.familyNameBalcão
person.familyNameMoutinho
person.familyNameMatos
person.familyNameNunes Vieira de Almeida
person.givenNameVictor
person.givenNameCarla
person.givenNameCarla
person.givenNameCristina Maria
person.identifier366700
person.identifier1536969
person.identifier.ciencia-idC314-A18C-931B
person.identifier.ciencia-idB61F-F356-80C6
person.identifier.ciencia-id721C-DA34-256E
person.identifier.ciencia-id0B1E-B91D-CBF4
person.identifier.orcid0000-0003-0772-2834
person.identifier.orcid0000-0003-1310-4696
person.identifier.orcid0000-0003-0617-3538
person.identifier.orcid0000-0002-8604-4594
person.identifier.ridI-2182-2012
person.identifier.ridM-7142-2013
person.identifier.scopus-author-id6603449856
person.identifier.scopus-author-id16064733800
person.identifier.scopus-author-id7004493818
person.identifier.scopus-author-id25722719400
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublicationcff7638e-1f33-4384-aa73-d3acc5cca5f8
relation.isAuthorOfPublicationd4b6d3e1-6d29-4fb4-97c7-abb2cf4c83b4
relation.isAuthorOfPublication27e47622-e356-40a6-a351-e8288fd646b3
relation.isAuthorOfPublication.latestForDiscoverycff7638e-1f33-4384-aa73-d3acc5cca5f8

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