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Publication
Natural oxidants and ageing: myth or paradox?
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Abstract(s)
Os danos oxidativos podem ser prevenidos in vivo através da actividade protectora de
antioxidantes biológicos (enzimáticos e não-enzimáticos). A importância dos antioxidantes
biológicos é tal que, na sua ausência a vida estaria continuamente sob a ameaça da
oxidação. Este fenómeno interfere com a estrutura, enovelamento e função das proteínas,
com a integridade dos lípidos membranares e com a estrutura do DNA; a oxidação resulta
também no processo de envelhecimento, através da acumulação de danos nas estruturas
subcelulares.
Oxidative damage can be prevented in vivo through the protective activity of biological antioxidants (enzymatic and non-enzymatic). The importance of the biological anti-oxidants is such that, in their absence, life would be continuously under threat from oxidation. This general phenomenon interferes with protein structure, folding and function, with the integrity of membrane lipids and also with the structure of DNA; furthermore, oxidation results in the onset of the aging process, through the accumulation of damages in subcellular structures.
Oxidative damage can be prevented in vivo through the protective activity of biological antioxidants (enzymatic and non-enzymatic). The importance of the biological anti-oxidants is such that, in their absence, life would be continuously under threat from oxidation. This general phenomenon interferes with protein structure, folding and function, with the integrity of membrane lipids and also with the structure of DNA; furthermore, oxidation results in the onset of the aging process, through the accumulation of damages in subcellular structures.
Description
Keywords
Antioxidantes Saúde Envelhecimento Stress oxidativo Carotenoides Antioxidants Health Aging Oxidative stress Carotenoids
Citation
Revista da Faculdade de Ciências da Saúde. Porto. ISSN 1646-0480. 4 (2007) 66-75.