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FAAH rs324420 polymorphism is associated with performance in elite rink-hockey players

2022-07-20Journal article Open access
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dc.contributor.authorSilva, Hugo-Henrique
dc.contributor.authorTavares, Valéria
dc.contributor.authorSilva, Maria Raquel
dc.contributor.authorNeto, Beatriz Vieira
dc.contributor.authorCerqueira, Fátima
dc.contributor.authorMedeiros, R.
dc.date.accessioned2022-07-28T15:47:48Z
dc.date.available2022-07-28T15:47:48Z
dc.date.issued2022-07-20
dc.description.abstractGenetic factors are among the major contributors to athletic performance. Although more than 150 genetic variants have been correlated with elite athlete status, genetic foundations of competition-facilitating behavior influencing elite performances are still scarce. This is the first study designed to examine the distribution of genetic determinants in the athletic performance of elite rink-hockey players. A total of 116 of the world’s top best rink-hockey players (28.2 ± 8.7 years old; more than 50% are cumulatively from the best four world teams and the best five Portuguese teams), who participated at the elite level in the National Rink-Hockey Championship in Portugal, were evaluated in anthropometric indicators/measurements, training conditions, sport experience and sport injuries history. Seven genetic polymorphisms were analyzed. Polymorphism genotyping was performed using the TaqMan® Allelic Discrimination Methodology. Rink-hockey players demonstrated significantly different characteristics according to sex, namely anthropometrics, training habits, sports injuries and genetic variants, such as Vitamin D Receptor (VDR) rs731236 (p < 0.05). The Fatty Acid Amide Hydrolase (FAAH) rs324420 A allele was significantly associated with improved athletic performance (AA/AC vs. CC, OR = 2.80; 95% Cl, 1.23–6.35; p = 0.014; p = 0.008 after Bootstrap) and confirmed as an independent predictor among elite rink-hockey players (adjusted OR = 2.88; 95% Cl, 1.06–7.80; p = 0.038). Our results open an interesting link from FAAH-related biology to athletic performance.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSilva H-H, Tavares V, Silva M-RG, Neto BV, Cerqueira F, Medeiros R. FAAH rs324420 Polymorphism Is Associated with Performance in Elite Rink-Hockey Players. Biology. 2022; 11(7):1076. https://doi.org/10.3390/biology11071076pt_PT
dc.identifier.doi10.3390/biology11071076pt_PT
dc.identifier.eissn2079-7737
dc.identifier.urihttp://hdl.handle.net/10284/11040
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.subjectElite athletept_PT
dc.subjectRink-hockeypt_PT
dc.subjectGenept_PT
dc.subjectPolymorphismpt_PT
dc.subjectSportpt_PT
dc.subjectPerformancept_PT
dc.subjectSuccesspt_PT
dc.titleFAAH rs324420 polymorphism is associated with performance in elite rink-hockey playerspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue7pt_PT
oaire.citation.startPage1076pt_PT
oaire.citation.titleBiologypt_PT
oaire.citation.volume11pt_PT
person.familyNameSilva
person.familyNameCerqueira
person.familyNameMedeiros
person.givenNameMaria Raquel
person.givenNameFátima
person.givenNameRui
person.identifier812695
person.identifier37604
person.identifier.ciencia-id2518-6117-FB25
person.identifier.ciencia-idCF14-52ED-5DA0
person.identifier.ciencia-idC51F-5DBE-9C51
person.identifier.orcid0000-0001-8170-3119
person.identifier.orcid0000-0003-4513-4654
person.identifier.orcid0000-0003-3010-8373
person.identifier.ridM-7557-2013
person.identifier.ridC-7938-2009
person.identifier.scopus-author-id56924197900
person.identifier.scopus-author-id6603346911
person.identifier.scopus-author-id7006241641
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication2705e35c-97f6-4de2-bbf1-d680342760e9
relation.isAuthorOfPublication5ffb7965-d9af-4ba1-a81b-b0aed28de206
relation.isAuthorOfPublication.latestForDiscovery5ffb7965-d9af-4ba1-a81b-b0aed28de206

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