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Coágulo A+-PRF convencional versus coágulo A+-PRF com protocolo PomPac: estudo comparativo do comprimento
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Advisor(s)
Abstract(s)
Objetivo: Este estudo teve por objetivo compreender se a temperatura a que a colheita sanguínea é acondicionada no protocolo Advanced Plus-Platelet Rich Fibrin (A+-PRF), interfere nos resultados dimensionais dos coágulos.
Materiais e Métodos: Dez voluntários, sem histórico de toma de anti-coagulantes e com intervenções cirúrgicas com tratamento com A+-PRF, foram submetidos a colheita de quatro tubos de sangue. Dois tubos colhidos sob protocolo convencional e outros dois sob protocolo PomPac. Após colheita procedeu-se à produção de coágulos segundo o protocolo de A+-PRF, previamente descrito na literatura (Ghanaati et al, 2014). Os coágulos (4x10 = 40) foram submetidos a registo de dimensões de comprimento. Posteriormente foi realizada análise estatística dos dados.
Resultados: A dimensão média dos coágulos provenientes do protocolo A+-PRF convencional foi de 29,10 milímetros (mm) e os provenientes do protocolo com Pompac foi de 34,35 mm (p<0,001; n=20). Para a dimensão máxima registou-se para o protocolo A+-PRF o valor de 35 mm e para o Protocolo A+-PRF com Pompac 41mm (p<0,001; n=20).
Conclusão: Este estudo permitiu concluir que o protocolo A+-PRF com Pompac permite obter coágulos com comprimento máximo e médio mais elevados que os obtidos com o protocolo A+-PRF convencional. Estes fatos fazem do protocolo A+-PRF com Pompac uma melhor escolha em detrimento do protocolo A+-PRF convencional no que respeita à quantidade de biomaterial disponível.
Purpose: This study aimed to understand the temperature at which the blood collection is stored in the Advanced Plus-Platelet Rich Fibrin (A+ -PRF) protocol, interferes with the dimensional results of clots. Materials and Methods: Ten volunteers, with no history of anticoagulants medication and undergoing surgical interventions with treatment with A+-PRF, underwent collection of four tubes of blood. Two tubes were collected under conventional protocol and another two under PomPac protocol. After collection, clots were produced according to the A+-PRF protocol, previously described in the literature (Ghanaati et al, 2014). The clots (4x10 = 40) were submitted to length dimension recording. Subsequently, statistical analysis of the data was performed. Results: The mean dimension of clots from the conventional A+-PRF protocol was 29,10 millimeter (mm) and those from the Pompac protocol was 34,35 mm (p<0.001; n=20). For the maximum dimension, the value of 35 mm was recorded for the A+-PRF protocol and 41 mm for the A+-PRF protocol with Pompac (p<0.001; n=20). Conclusion: This study allowed us to conclude that the A+-PRF protocol with Pompac allows to obtain clots with higher maximum and average length than those obtained with the conventional A+-PRF protocol. These facts make the A+-PRF protocol with Pompac a better choice over the conventional A+-PRF protocol in terms of the amount of biomaterial available.
Purpose: This study aimed to understand the temperature at which the blood collection is stored in the Advanced Plus-Platelet Rich Fibrin (A+ -PRF) protocol, interferes with the dimensional results of clots. Materials and Methods: Ten volunteers, with no history of anticoagulants medication and undergoing surgical interventions with treatment with A+-PRF, underwent collection of four tubes of blood. Two tubes were collected under conventional protocol and another two under PomPac protocol. After collection, clots were produced according to the A+-PRF protocol, previously described in the literature (Ghanaati et al, 2014). The clots (4x10 = 40) were submitted to length dimension recording. Subsequently, statistical analysis of the data was performed. Results: The mean dimension of clots from the conventional A+-PRF protocol was 29,10 millimeter (mm) and those from the Pompac protocol was 34,35 mm (p<0.001; n=20). For the maximum dimension, the value of 35 mm was recorded for the A+-PRF protocol and 41 mm for the A+-PRF protocol with Pompac (p<0.001; n=20). Conclusion: This study allowed us to conclude that the A+-PRF protocol with Pompac allows to obtain clots with higher maximum and average length than those obtained with the conventional A+-PRF protocol. These facts make the A+-PRF protocol with Pompac a better choice over the conventional A+-PRF protocol in terms of the amount of biomaterial available.
Description
Keywords
A+-PRF A-Platelet-rich fibrin Blood collection PomPac Temperature