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- Ethnopharmacological notes about ancient uses of medicinal plants in Trás-os-Montes (northern of Portugal)Publication . Neves, José Manuel Gomes da Silva; Matos, Carla; Moutinho, Carla; Queiroz, Glória; Gomes, Lígia RebeloAim of the study In order to preserve the ancestral knowledge, an ethnopharmacological study has been carried out in two councils belonging to Trás-os-Montes region a small area located in the northern of Portugal. In that area, medicinal plants, most of the species wild, are still in use among farmers, shepherds and other people who live far from villages and built-up areas. Materials and methods Among the 46 people that were interviewed (mean age of 66 years old), 88 species belonging to 42 families of vascular plants were identified for treatment of various human ailments. An ethnopharmacological report is made consisting of species names, vernacular names, popular uses of the plants and their pharmacological properties. Results and conclusion The most dominant family is Lamiaceae (18%) and the most frequently part of the plant used for the treatment of diseases are leaves (37.9%). The largest number of taxa is used to treat gastrointestinal disorders (73.9%).
- Actividade antioxidante e avaliação in vitro da citotoxicidade de extractos aquosos de folhas de mentha x piperitaPublication . Neves, José Manuel Gomes da Silva; Matos, Carla; Moutinho, Carla; Gomes, Lígia Rebelo; Teixeira, TâniaNeste estudo apresentam-se os resultados referentes à avaliação do potencial anti-oxidante de extractos aquosos de Menta x piperita recolhida da região de trás-os-montes. A capacidade anti-oxidante foi testada pelo método DppH•, tendo sido também feita a quantificação dos compostos fenólicos totais nos extractos pelo método de Folin-ciocalteu, apontados como os responsáveis pelas propriedades antioxidantes da planta. Adicionalmente, apresentam- se os resultados relativos à avaliação citotoxicidade dos mesmos extractos através de testes de citotoxicidade in vitro, utilizando como organismo modelo tetrahymena pyriformis (com viabilidade avaliada pelo ensaio colorimétrico mtt). The aim of the present study is to investigate the antioxidant potential of aqueous extracts of Menta x piperita from trás-os-montes by the DppH• method, as well as to quantify the total phenolic compounds in the extracts by the Folin-ciocalteu method, probably responsible for the plant antioxidant properties. Additionally, the research work presented herein seeks to assess the effects of Menta x piperita through a series of in vitro cytotoxicity tests, using tetrahymena pyriformis as model organism. Viability will be evaluated by the colorimetric mtt assay.
- Usos populares de plantas medicinais da flora transmontanaPublication . Neves, José Manuel Gomes da Silva; Matos, Carla; Moutinho, Carla; Gomes, Lígia RebeloNeste trabalho é apresentado um estudo sobre o uso tradicional das plantas medicinais de dois concelhos da região de Trás-os-Montes. Durante o estudo, foram obtidos resultados relativos às plantas com maior uso medicinal e suas aplicações terapêuticas bem como as partes da planta mais usadas de 88 espécies pertencentes a 47 famílias de plantas indígenas. As propriedades terapêuticas mais referenciadas são os efeitos diurético, antiasténico e como vulnerário. Partindo de um relatório etnofarmacológico de várias plantas serão, posteriormente, seleccionadas aquelas que, tendo larga aplicação na medicina tradicional, não tenham sido estudadas do ponto de vista bioquímico e de actividade terapêutica. In this work a study of folk use of the medicinal plants of two councils bellowing to Trás-os-Montes region is presented. During the study, data for 88 species were obtained belonging to 47 families of vascular plants. The most report therapeutic properties are as diuretic, as anti-asthenia and as vulnerary. From an ethnopharmacological report done, will be subsequently selected those plants that, having, not only, a wide range of usage in traditional medicine but also, have not yet been studied in biochemical or therapeutic activity terms.