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- Marine-derived compounds in nanosystems for skin care applicationsPublication . Brito, Alice Margarida Fernandes; Silva, Ana CatarinaThe marine environment is an extensive reservoir of biodiversity and a rich source of bioactive compounds with significant potential for application in skin care. This review examines compounds isolated from algae, crustaceans, sea cucumbers, and marine sponges, including pigments (astaxanthin, fucoxanthin, β-carotene, lutein, lycopene, and phycocyanin), polysaccharides (fucoidans, alginate, and chitosan), proteins (collagen), fat-soluble vitamins (A and E), and mycosporine-like amino acids. These compounds exhibit multifunctional properties, such as antioxidant, anti-inflammatory, photoprotective, moisturizing, and anti-aging, making them highly valuable for the development of next-generation cosmetic formulations. Incorporation of these bioactives into nanosystems enhances their chemical stability, bioavailability, and skin penetration, thereby increasing the efficacy of cosmetic products while addressing the rising demand for natural and sustainable alternatives. This review highlights the critical role of scientific and technological advances in developing innovative nanocosmetic formulations, positioning marine-derived resources as strategic contributors to the evolution of the cosmetic industry. Furthermore, the implementation of environmentally responsible and sustainable extraction methods is essential to preserve marine ecosystems and ensure the long-term viability of these valuable resources.