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- Estudo comparativo das taxas de filtração glomerular obtidas através da cistatina C e creatinina no acompanhamento da função renal em pacientes com bexiga neurogénica por infecção pelo HTLV-IPublication . Araújo, Luciana Guedes Carvalho de; Catita, José; Barreira, SérgioA avaliação da função renal é imprescindível na prática clínica para a garantia da homeostase. A busca de marcadores sensíveis aos primeiros indícios de lesão renal é um importante desafio da medicina laboratorial, especialmente em grupos mais suscetíveis, tais como diabéticos, portadores de doenças cardiovasculares e doenças neurológicas, dentre elas, a mielopatia por HTLV-I. Na mielopatia associada ao HTLV/paraparesia espástica tropical (HTLV-associated myelopathy/tropical spastic paraparesis – HAM/TSP) observa-se disfunção vesical com origem no comprometimento da medula toracolombar resultando, na maioria das vezes, em bexiga neurogénica. Diante deste contexto, é recomendado avaliar periodicamente a função renal do portador sintomático de HTLV-I com bexiga neurogénica a fim de melhorar o manejo urológico e preservar a função renal. Este trabalho objetivou comparar os resultados de cistatina C e da creatinina sérica, através da avaliação de dados retrospectivos em prontuário eletrónico, de pacientes adultos portadores de HAM/TSP com diagnóstico de bexiga neurogénica atendidos no Hospital SARAH Salvador (Bahia, Brasil) no período de 2002 a 2018. Este estudo realizou análise comparativa das taxas de filtração glomerular (TFG) obtidas através da cistatina-C e creatinina usando as fórmulas CKD-EPI recomendadas pelo guideline de doenças renais crónicas da KDIGO. Conclui-se que os resultados de TFG não demonstraram concordância entre si e ressalta-se que os resultados obtidos pela cistatina apresentam resultados inferiores de TFG antecipando as condutas clínicas de manejo do paciente.
- Profitability in a social business: an environmental analysis of the social sector in PortugalPublication . van Steenbergen, Daisy Isabella; Ramos, PauloAs it is described by Henderson, the concept of strategy can be traced back to ancient times with the central idea being: to gain advantage over someone or something (Henderson, 1989). In order to build a successful strategy for any type of business, a strategic analysis needs to be performed. A strategic analysis exists of multiple elements, but it always starts with environmental scanning. This research focuses on that very first step by conducting an environmental analysis. It is a strategic tool that identifies all the external and internal elements, which could possibly affect the organization's performance. The analysis entails assessing the level of threat or opportunity that factors might present. To achieve this, a SWOT analysis was conducted in combination with other tools, such as PESTEL, Porter´s five forces and the Power-interest matrix. These tools were analysed by using the gathered research data. The data collection was divided into two parts: a desk research, where close attention was paid to literature review and a field research, where experts were interviewed. Both focused on analysing the Portuguese social sector. To structure this data collection five categories were determined: The benchmark between Portugal and the Netherlands; The financial mechanism; The Portuguese social care system; The target group and the critical success factors. The aim of this research was not to provide all the final and conclusive answers, it was merely to explore the research topic with varying levels of depth. Additionally, this research tended to tackle new problems on which little or no previous research has been done by combining and elaborating well known models, such as PESTEL, Porter´s 5 forces and SWOT. The research problem of this dissertation can be described as followed: to determine the possibilities of starting a successful commercial business within the social welfare sector of Portugal.