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Ultra-trace elements in human health: selenium, chromium, molybdenum, cobalt, boron and iodine

2019-11Journal article Restricted access
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dc.contributor.authorSilva, Carla Sousa e
dc.contributor.authorMoutinho, Carla
dc.contributor.authorFerreira da Vinha, Ana
dc.contributor.authorMatos, Carla
dc.date.accessioned2019-12-11T11:14:17Z
dc.date.available2019-12-11T11:14:17Z
dc.date.issued2019-11
dc.description.abstractEssential ultra-trace elements have an essential role in many physiological processes, regulating enzymes and metabolic pathways, being fundamental for growth, development, muscle and nerve function, normal cellular functioning, and synthesis of some hormones and connective tissue. Nevertheless, excessive levels of these elements can also lead to health problems, as neoplastic diseases. Another field of interest, that has been capturing researcher’s attention for several years, is the possibility of development of pharmacologically active compounds base in these ultra-trace minerals, as anticancer, anti-inflammatories, antidiabetic or antimicrobial agents. This article aims to review the main effects of ultra-trace elements in human health, namely selenium, chromium, molybdenum, cobalt, boron and iodine, focusing on the physiopathology and consequences of deficiency and/or excess of these elements. Also, it offers an overview of research information published in recent years concerning the use of these metals in compounds that show promising pharmacological activities.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.issn2454-2008
dc.identifier.urihttp://hdl.handle.net/10284/8291
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherHuman Journalspt_PT
dc.relation.publisherversionhttp://ijsrm.humanjournals.com/ultra-trace-elements-in-human-health-selenium-chromium-molybdenum-cobalt-boron-and-iodine/pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectUltra-trace elementspt_PT
dc.subjectMineralspt_PT
dc.subjectHealthpt_PT
dc.subjectMetal-based drugspt_PT
dc.subjectBody functionpt_PT
dc.titleUltra-trace elements in human health: selenium, chromium, molybdenum, cobalt, boron and iodinept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage72pt_PT
oaire.citation.issue1
oaire.citation.startPage45pt_PT
oaire.citation.titleInternational Journal of Science and Research Methodologypt_PT
oaire.citation.volume14pt_PT
person.familyNameSilva
person.familyNameMoutinho
person.familyNameMendes Ferreira da Vinha
person.familyNameMatos
person.givenNameCarla
person.givenNameCarla
person.givenNameAna Cristina
person.givenNameCarla
person.identifier1536969
person.identifier.ciencia-id2E1D-05DF-E0DB
person.identifier.ciencia-idB61F-F356-80C6
person.identifier.ciencia-id011A-FCBD-DC66
person.identifier.ciencia-id721C-DA34-256E
person.identifier.orcid0000-0001-6467-4766
person.identifier.orcid0000-0003-1310-4696
person.identifier.orcid0000-0002-6116-9593
person.identifier.orcid0000-0003-0617-3538
person.identifier.ridD-8159-2013
person.identifier.ridM-7142-2013
person.identifier.scopus-author-id16064733800
person.identifier.scopus-author-id7004493818
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication741eff47-ffdf-4a5f-b763-3ada0062b1b8
relation.isAuthorOfPublicationcff7638e-1f33-4384-aa73-d3acc5cca5f8
relation.isAuthorOfPublicationb09696c0-d5ea-4218-a5e4-63a3f6288d83
relation.isAuthorOfPublicationd4b6d3e1-6d29-4fb4-97c7-abb2cf4c83b4
relation.isAuthorOfPublication.latestForDiscoveryd4b6d3e1-6d29-4fb4-97c7-abb2cf4c83b4

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