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Antimicrobial potential of cannabinoids: a scoping review of the past 5 years

2025-02-02Recensão Acesso aberto
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datacite.subject.fosCiências Médicas
datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorCoelho, Maria João
dc.contributor.authorAraújo, Maria Duarte
dc.contributor.authorCarvalho, Marcia
dc.contributor.authorLopes Cardoso, Inês
dc.contributor.authorManso, Maria da Conceição
dc.contributor.authorPina, Cristina
dc.date.accessioned2026-05-11T13:01:11Z
dc.date.available2026-05-11T13:01:11Z
dc.date.issued2025-02-02
dc.description.abstractIn the scenario of fighting bacterial resistance to antibiotics, natural products have been extensively investigated for their potential antibacterial activities. Among these, cannabinoids—bioactive compounds derived from cannabis—have garnered attention for their diverse biological activities, including anxiolytic, anti-inflammatory, analgesic, antioxidant, and neuroprotective properties. Emerging evidence suggests that cannabinoids may also possess significant antimicrobial properties, with potential applications in enhancing the efficacy of conventional antimicrobial agents. Therefore, this review examines evidence from the past five years on the antimicrobial properties of cannabinoids, focusing on underlying mechanisms such as microbial membrane disruption, immune response modulation, and interference with microbial virulence factors. In addition, their synergistic potential, when used alongside standard therapies, underscores their promise as a novel strategy to address drug resistance, although further research and clinical trials are needed to validate their therapeutic use. Overall, cannabinoids offer a promising avenue for the development of innovative treatments to combat drug-resistant infections and reduce the reliance on traditional antimicrobial agents.eng
dc.identifier.citationCoelho, M. J., Araújo, M. D., Carvalho, M., Cardoso, I. L., Manso, M. C., & Pina, C. (2025). Antimicrobial potential of cannabinoids: A scoping review of the past 5 years. Microorganisms, 13(2), 325. https://doi.org/10.3390/microorganisms13020325
dc.identifier.doi10.3390/microorganisms13020325
dc.identifier.issn20762607
dc.identifier.urihttp://hdl.handle.net/10284/15420
dc.language.isoeng
dc.peerreviewedyes
dc.publisherMDPI
dc.relation.hasversionhttps://www.mdpi.com/2076-2607/13/2/325
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectCannabinoids
dc.subjectCannabis
dc.subjectAntimicrobial potential
dc.subjectAntibacterial
dc.subjectAntiviral
dc.subjectAntifungal
dc.titleAntimicrobial potential of cannabinoids: a scoping review of the past 5 yearseng
dc.typereview
dspace.entity.typePublication
oaire.citation.issue2
oaire.citation.startPage325
oaire.citation.titleMicroorganisms
oaire.citation.volume13
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameCoelho
person.familyNameCarvalho
person.familyNameLopes Cardoso
person.familyNameManso
person.familyNamePina
person.givenNameMaria João
person.givenNameMarcia
person.givenNameInês
person.givenNameMaria da Conceição
person.givenNameCristina
person.identifier2017111
person.identifier.ciencia-id8B10-171E-E63E
person.identifier.ciencia-idF21F-16B4-3715
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person.identifier.ridD-5999-2013
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person.identifier.scopus-author-id7201413997
person.identifier.scopus-author-id54973754300
person.identifier.scopus-author-id57196702148
person.identifier.scopus-author-id6504669461
relation.isAuthorOfPublication0c815556-3dbb-4664-a135-908c27447880
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