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Publication
A relação da periodontite com a artrite reumatoide: revisão narrativa
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 37920 | 1021.44 KB | Adobe PDF |
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Abstract(s)
A possível associação entre a periodontite e a artrite reumatoide tem sido investigada devido a numerosas semelhanças nas suas características imunológicas e patológicas. Ambas as doenças levam destruição de tecidos moles e duros como resultado de processos inflamatórios e a sua ditada por uma rede de inflamatórias com os seus mediadores. Para além disso, partilham também alguns fatores de risco, como a predisposição genética e o consumo de tabaco. Esta revisão tem como principal objetivo expor a informação atual sobre os aspetos imunopatológicos e os mecanismos que ligam estas duas doenças, bem como o impacto que os tratamentos de uma doença exercem sobre a outra.
The possible association between periodontitis and rheumatoid arthritis has been investigated due to numerous similarities in their immunological and pathological characteristics. Both diseases lead to the destruction of soft and hard tissues as a result of inflammatory processes, and their pathogenesis is dictated by a network of inflammatory cells with their mediators. Additionally, they also share some risk factors, such as genetic predisposition and tobacco consumption. The main purpose of this review is to present current information on the immunopathological aspects and mechanisms linking these two diseases, as well as the impact that the treatments of one disease have on the other.
The possible association between periodontitis and rheumatoid arthritis has been investigated due to numerous similarities in their immunological and pathological characteristics. Both diseases lead to the destruction of soft and hard tissues as a result of inflammatory processes, and their pathogenesis is dictated by a network of inflammatory cells with their mediators. Additionally, they also share some risk factors, such as genetic predisposition and tobacco consumption. The main purpose of this review is to present current information on the immunopathological aspects and mechanisms linking these two diseases, as well as the impact that the treatments of one disease have on the other.
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Keywords
Periodontite Artrite reumatoide Periodontitis Perda de osso alveolar Rheumatoid arthritis Reabsorção óssea Inflamação Citocinas Alveolar bone loss Bone resorption Inflammation Cytokines