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| PPG_38803 | 394.22 KB | Adobe PDF |
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Advisor(s)
Abstract(s)
O cancro oral é um dos cancros mais comuns no mundo, sendo um problema de saúde pública altamente relevante, afetando principalmente os lábios e a cavidade oral. É uma doença evitável, onde o tabagismo e o consumo de álcool, considerados os principais fatores de risco, estão presentes em 90% dos casos, tendo efeito sinérgico. O álcool pode atuar tanto como um fator de risco localmente quanto sistemicamente. As opções de tratamento do cancro oral incluem cirurgia, radioterapia e quimioterapia. Até hoje não há biomarcadores específicos para o cancro oral.
O objetivo deste estudo é descrever o consumo de álcool como um fator de risco estabelecido e potencialmente modificável para o cancro oral. O álcool está causalmente associado ao cancro de orofaringe e laringe, cancro de esófago entre outros tipos de cancro. Mesmo o uso modesto de álcool pode aumentar o risco de cancro, porém maiores riscos são observados com o uso prolongado e grande quantidade.
Oral cancer is one of the most common cancers in the world and a highly relevant problem of global public health, affecting mainly lips and oral cavity. It is a preventable disease, where smoking and alcohol, considered major risk factors, are present in 90% of cases, having them both a synergic effect. Alcohol can act as a risk factor both locally and systemically. Treatment options of oral cancer include surgery, radiotherapy and chemotherapy. Until today there are no specific biomarkers for oral cancer. The aim of this study is to describe alcohol consumption as an established and potentially modifiable risk factor for oral cancer. Alcohol is causally associated with oropharyngeal and larynx cancer, esophageal cancer, among other types of cancer. Even modest use of alcohol may increase cancer risk, but the greatest risks are observed with heavy, long-term use.
Oral cancer is one of the most common cancers in the world and a highly relevant problem of global public health, affecting mainly lips and oral cavity. It is a preventable disease, where smoking and alcohol, considered major risk factors, are present in 90% of cases, having them both a synergic effect. Alcohol can act as a risk factor both locally and systemically. Treatment options of oral cancer include surgery, radiotherapy and chemotherapy. Until today there are no specific biomarkers for oral cancer. The aim of this study is to describe alcohol consumption as an established and potentially modifiable risk factor for oral cancer. Alcohol is causally associated with oropharyngeal and larynx cancer, esophageal cancer, among other types of cancer. Even modest use of alcohol may increase cancer risk, but the greatest risks are observed with heavy, long-term use.
Description
Keywords
Cancro oral Consumo de álcool Fator de risco Oral cancer Alcohol drinking Risk factor
