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Pharmaceutical approaches for optimizing oral anti-inflammatory delivery systems

dc.contributor.authorLopes, Carla Martins
dc.contributor.authorOliveira, R.
dc.contributor.authorSilva, Ana Catarina
dc.date.accessioned2020-10-13T08:25:40Z
dc.date.available2020-10-13T08:25:40Z
dc.date.issued2011-06-01
dc.date.updated2020-07-24T17:07:07Z
dc.description.abstractThe purpose of the present review is to compile the recent literature in the field of anti-inflammatory treatments, with special focus to the state-of-the-art on pharmaceutical approaches for optimizing oral administration. Attending to the drawbacks associated with the use of these types of drugs, the development of oral modulated release formulations is highly desirable in order to achieve improved therapeutic efficacy and patient compliance. Several technological systems and their advantages in modulated and targeted drug releases (gastroretention or colonic release) have been described: matrix systems, coated dosage forms, osmotic pressure based formulations, prodrugs, colloidal carriers, microparticles and other carriers. These new approaches seem to be promising and have been considered by pharmaceutical companies.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.2174/1871523011109030154pt_PT
dc.identifier.issn1871-5230
dc.identifier.slugcv-prod-1252841
dc.identifier.urihttp://hdl.handle.net/10284/9048
dc.language.isoengpt_PT
dc.publisherBentham Science Publisherspt_PT
dc.subjectAnti-inflammatory drugspt_PT
dc.subjectMatrix systemspt_PT
dc.subjectCoated systemspt_PT
dc.subjectOsmotic Systemspt_PT
dc.subjectProdrugspt_PT
dc.subjectColloidal carrierspt_PT
dc.subjectMicroparticlespt_PT
dc.subjectGastroretentive systemspt_PT
dc.subjectColon systemspt_PT
dc.titlePharmaceutical approaches for optimizing oral anti-inflammatory delivery systemspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage165pt_PT
oaire.citation.issue3pt_PT
oaire.citation.startPage154pt_PT
oaire.citation.titleAnti-inflammatory & Anti-Allergy Agents in Medicinal Chemistrypt_PT
oaire.citation.volume10pt_PT
person.familyNameLopes
person.familyNameSilva
person.givenNameCarla
person.givenNameAna Catarina
person.identifier953153
person.identifier.ciencia-id901D-160C-633E
person.identifier.ciencia-id5C1D-ED22-0D64
person.identifier.orcid0000-0001-5080-032X
person.identifier.orcid0000-0001-6923-0232
person.identifier.ridM-4689-2016
person.identifier.ridF-1875-2017
person.identifier.scopus-author-id26649517700
person.identifier.scopus-author-id57028697500
rcaap.cv.cienciaid901D-160C-633E | Carla Martins Lopes
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationd2a48cfe-9258-4916-99be-bbcb710f6605
relation.isAuthorOfPublication67e7f707-32ec-444a-a20d-a17f8e6e7c21
relation.isAuthorOfPublication.latestForDiscoveryd2a48cfe-9258-4916-99be-bbcb710f6605

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